Samsung Linagliptin Duo Tablet 2.5/1000mg

Adult dose

The dosage of this medication is determined based on the maximum recommended doses of each ingredient, which are linagliptin 2.5 mg and metformin 1000 mg, not exceeding twice daily dosing, considering the patient's current therapy, efficacy, and tolerance. This medication is administered twice daily with meals. 1. If currently not being treated with metformin: As an initial dose, take this medication 2.5/500 mg 1 tablet twice daily.

This medication can cause a serious metabolic complication called lactic acidosis, hence it should not be administered to patients with impaired kidney function or liver dysfunction. Patients with an allergy to any component of this medication or those with specific conditions such as type 1 diabetes, diabetic ketoacidosis, acute myocardial infarction, etc., should not use this medication. Due to the risk of hypoglycemia, careful monitoring of blood sugar levels is necessary when used alongside insulin or sulfonylureas, and doses may need to be adjusted if needed. This medication should be temporarily discontinued during situations that may lead to rapid changes in kidney function, such as acute renal function deterioration, severe infections, pre- and post-operative states, and before and after iodine contrast examinations. Pregnant or nursing women are advised against taking this medication, and those planning to become pregnant should consult with a physician. Elderly patients may experience reduced kidney function, and they should regularly have their kidney function checked and adjust the dosage if necessary. Possible side effects include gastrointestinal disorders, abdominal pain, diarrhea, taste disturbances, nausea, vomiting, abdominal pain, oral ulcer formation, abnormal liver function tests, hepatitis, pruritus, erythema, rash, severe and disability-affected arthralgia, rhabdomyolysis, elevated lipase, increased amylase, decreased and deficient vitamin B12, elevated serum triglycerides, increased creatinine, and increased creatine phosphokinase. Long-term use may lead to vitamin B12 deficiency, necessitating blood tests for monitoring. There may be interactions with other medications, thus patients should inform their doctor or pharmacist of any other medications they are taking. This medication is not recommended for children, and the effects on driving or operating machinery are unknown, hence caution is advised. In cases of overdose, there is a risk of lactic acidosis, and immediate medical attention is required; it should be stored out of reach of children and kept away from moisture.

Serious side effects

• Lactic acidosis
• urticaria
• angioedema
• bullous pemphigoid
• acute pancreatitis
• angioedema
• urticaria
• angioedema
• angioedema
• angioedema

Mild side effects

Nasopharyngitis, hypersensitivity, hypoglycemia, taste disturbance, cough, decreased appetite, diarrhea, constipation, nausea, vomiting, abdominal pain, oral ulcer formation, abnormal liver function tests, hepatitis, pruritus, erythema, rash, severe arthralgia accompanied by disability, rhabdomyolysis, increased lipase, increased amylase, decreased and deficient vitamin B12, increased serum triglycerides, increased creatinine, increased creatine phosphokinase, male pattern baldness,

This medication is sensitive to air and moisture; therefore, it should be stored in a tightly sealed container. Additionally, it is important to keep it at room temperature between 1°C and 30°C to maintain its efficacy.

Appearance

Bright pink oval film-coated tablet

Package unit

60 tablets/PTP[(10 tablets/PTP×6)]