Esomeprazole Magnesium Trihydrate 20 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1. Gastroesophageal Reflux Disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks - Maintenance therapy to prevent recurrence of esophagitis: 20 mg once daily - Treatment of symptoms in gastroesophageal reflux disease without esophagitis: 20 mg once daily, and if symptoms persist, the same

Children's dosage

Adolescents aged 12 years and older - Treatment of gastroesophageal reflux disease: 40 mg once daily for 4 weeks - Treatment of symptoms of gastroesophageal reflux disease without esophagitis: 20 mg once daily

This medication should not be administered to specific patients. For example, it should not be used in patients with known allergies to this medication or its components, including benzimidazole derivatives, or those who have previously shown such reactions. Care should also be taken in patients who are taking amoxicillin or clarithromycin for the eradication of Helicobacter pylori, in case of allergies to these antibiotics. This medication should particularly not be given to patients taking specific heart-related medications or those with a history of myocardial infarction, and to nursing mothers. This medication contains the dye E102, and those with sensitivity or allergy history to this component should use it cautiously. Various adverse reactions may occur while taking this medication, with common symptoms including headache, abdominal pain, diarrhea, and nausea; rare occurrences of blood disorders or severe allergic reactions may also arise. Long-term use may result in electrolyte imbalance, such as hypomagnesemia, necessitating regular check-ups. Furthermore, as this medication reduces gastric acid, the risk of bacterial infections in the gastrointestinal tract may increase, and the risk of fractures may heighten, so caution is advised in patients at risk of osteoporosis. There are many drug interactions with this medication; when taken with digoxin, warfarin, methotrexate, etc., strict adherence to the physician's instructions is required, and it is advisable not to use it in conjunction with certain antiviral medications. During pregnancy, the safety has not been fully established, thus it should be used cautiously; it is recommended not to use this medication during breastfeeding. In cases of overdose, as there are no specific antidotes, symptoms should be monitored and proper treatment should be administered. Lastly, this medication should be kept out of the reach of children and should not be transferred to another container to maintain its quality.

Serious side effects

Angioedema, anaphylactic reactions, shock, urticaria, severe swelling (edema), difficulty breathing, bronchospasm, fever, jaundice, hepatitis, hepatic failure, encephalopathy, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, eosinophilia and systemic symptoms accompanied drug reactions (DRESS syndrome), severe skin reactions, rhabdomyolysis, seizures, altered consciousness, visual disturbances, paralysis, severe

Mild side effects

• Headache
• dizziness
• confusion
• insomnia
• anxiety
• depression
• aggressiveness
• hallucinations
• drowsiness
• taste disorder

This medication should be stored in a tightly closed container to prevent air or moisture from entering. The storage temperature should be room temperature between 1 and 30 degrees Celsius.

Appearance

Pale pink round film-coated tablet

Package unit

28 tablets (14 tablets/PTP X 2)