Pioglionmet Tablet 15/850 milligrams

Adult dosage

This medication is generally administered divided with meals to reduce gastrointestinal adverse reactions due to metformin. Dosage should be individualized not exceeding the maximum doses of pioglitazone 30mg and metformin 2500mg. The initial dose should be based on the patient's current treatment regimen, starting with one tablet daily and gradually adjusting the dosage according to the therapeutic response. For patients transitioning from the combination therapy of pioglitazone and metformin, adjustments should be made appropriately.

This medication helps in controlling blood sugar levels. However, it should not be administered to patients with impaired renal function or severe heart failure. Moreover, patients with liver dysfunction should also avoid using this medication. It can cause serious side effects such as lactic acidosis; hence, if symptoms such as shortness of breath, muscle pain, fatigue, or abdominal pain occur, immediate consultation with a doctor is necessary. Excessive alcohol consumption increases the risk of side effects, so it is advisable to avoid alcohol during treatment. This medication may exacerbate heart failure symptoms, so careful observation of symptoms like weight gain, edema, and shortness of breath is required. Additionally, patients with a history of bladder cancer should weigh the risks and benefits carefully when using this medication. Pregnant or breastfeeding women should not take this medication, and its safety in pediatric patients has not been established. Regular monitoring of blood sugar, renal function, liver function, and blood tests should be conducted to ensure no abnormalities occur during treatment. When taking this medication with others, it is important to consult a doctor or pharmacist for potential interactions. In the case of overdose, immediate medical attention is necessary. Finally, this medication should be taken regularly alongside meals and exercise, while being cautious of hypoglycemia or other adverse reactions during treatment.

Serious side effects

Severe lactic acidosis, hypoglycemia, acute renal dysfunction, lactic acidosis that may occur in cardiopulmonary diseases and septic conditions, hypothermia, hypotension, resistive bradyarrhythmias, congestive heart failure, symptoms and signs of heart failure (including excessive and rapid weight change, shortness of breath, edema), bladder cancer, jaundice, liver failure, severe edema, hypoxic conditions, acute renal failure, severe allergic reactions, serious skin adverse reactions, respiratory

Mild side effects

• Upper respiratory tract infection
• diarrhea
• nausea
• headache
• urinary tract infection
• sinusitis
• dizziness
• lower limb edema
• weight gain
• muscle pain

This medication should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain the storage temperature between 1 and 30 degrees Celsius room temperature.

Appearance

White to pale white oval film-coated tablet

Package unit

30 tablets/PTP[(10 tablets/PTPX3)]