Question 1

What are the indications and effects of Rasagiline Tablets 0.5 mg (Rasagiline Mesylate)?

Accepted Answer

This medicine is used for the treatment of idiopathic Parkinson's disease. Initially, it is used alone or as an adjunct to dopamine agonists. Additionally, it is used as an adjunct to levodopa for patients with motor fluctuations known as 'end of dose fluctuations.' This helps to effectively improve the motor symptoms of Parkinson's disease.

Question 2

What are the dosage and administration instructions for Rasagiline Tablets 0.5 mg (Rasagiline Mesylate)?

Accepted Answer

This medicine is administered orally to adults once daily as monotherapy or adjunctive therapy.
1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily.
2) Adjunctive therapy to levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If well tolerated and an adequate clinical response is not achieved, the dose may be increased to 1mg once daily.
This medicine may be taken with or without food.

Question 3

What are the side effects of Rasagiline Tablets 0.5 mg (Rasagiline Mesylate)?

Accepted Answer

Influenza, skin cancer, leukopenia, allergy, appetite loss, depression, hallucinations, headache, cerebrovascular accident, conjunctivitis, dizziness, angina, myocardial infarction, rhinitis, abdominal distension, dermatitis, vesicular rash, musculoskeletal pain, neck pain, arthritis, urgency, fever, fatigue, peripheral edema, falls, arthralgia, low back pain, cough, insomnia, upper respiratory infection, orthostatic hypotension, nausea, constipation, vomiting, dry mouth, diarrhea, abdominal pain, dyspepsia, hernia, infection, gingivitis, accidental injury, weight loss, tendinitis, movement disorders, drowsiness, sensory disturbances, ataxia, muscle tone abnormalities, myasthenia, anorexia, abnormal dreams, respiratory difficulties, rash, hyperhidrosis, petechiae, melanoma, confusion, carpal tunnel syndrome, balance disorders, hypotension, pathological gambling, increased libido, hypersexuality, compulsive spending or purchasing, binge eating, compulsive eating, excessive drowsiness, acute renal failure, malignant hyperthermia, systemic weakness, pulmonary tuberculosis, semi-coma, gait disorders, ocular motor seizures, facial paralysis, spinal canal stenosis, worsening of Parkinson's disease, subdural hemorrhage, pneumonia, spinal fractures, rib fractures, tendon injuries, pelvic fractures, leg fractures, upper limb fractures, lower back pain, knee arthroplasty, herniated disc, hypoglycemia, weight loss, dysuria, hematuria, frequent urination, low urine output, nocturia, urinary incontinence, vaginitis, conjunctival hyperemia, diplopia, floaters, visual impairment, skin hypertrophy, palpitations, arrhythmia, gastrointestinal discomfort, gastroesophageal reflux, excessive salivation, irritable bowel syndrome, fissured tongue, increased bowel movements, unspecified gastrointestinal disease, esophagitis, hyperacidity, gastroesophageal reflux disease, gastric irritation, gastritis, intestinal motility disorders, periodontitis, Helicobacter pylori gastritis, anemia, leg pain, chest pain, syncope, periorbital edema, facial flushing, pain, delirium, sleep disorders, aggression, amnesia, memory impairment, lethargy, sleep talking, psychosexual disorders, paresthesia of the skin, tremor, freezing phenomena, limb tremors, dystonic muscle spasms, leg cramps, polyuria, tremors, stuttering, speech disorders, language disorders, pruritus, urticaria, eyelid skin disorders, abscess, hair loss, contusion, abnormal sputum, increased sputum, cold, bronchitis

Question 4

What precautions should be taken when using Rasagiline Tablets 0.5 mg (Rasagiline Mesylate)?

Accepted Answer

This medicine should not be used by patients who are allergic to the active ingredient or any other components.
Patients currently taking or who have recently stopped taking other MAO inhibitors or certain analgesics and cough medications should not take this medicine.
It is safe not to use this medicine in patients with moderate to severe liver impairment.
Various side effects such as headache, dizziness, nausea, and skin rash may occur when taking this medicine; consult a doctor if any abnormal symptoms occur.
Particularly, in Parkinson's patients, there may be mental symptoms such as hallucinations or depression, so caution is required.
This medicine may affect blood pressure, and symptoms of hypertensive crisis or hypotension may occur; thus, blood pressure management should be monitored.
When taken with dopaminergic treatments, drowsiness or sudden sleep episodes may occur, so caution should be exercised when driving or operating machinery.
Women who are pregnant or breastfeeding should consult a professional before using this medicine.
It is advisable not to use it in children as safety and efficacy have not been established.
Severe side effects may occur in case of overdose, so the prescribed dosage should be strictly adhered to.
This medicine has many drug interactions, so inform your doctor or pharmacist of any other medications you are taking.
Store it in a cool place out of reach of children and do not transfer it to another container.

Rasagiline Tablets 0.5 mg (Rasagiline Mesylate)

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