Medication info
Rasagiline Tablets (Rasagiline Mesylate)

Rasagiline Tablets (Rasagiline Mesylate)

Prescription medicationTabletOral
Ingredient · strength
Rasagiline Mesylate›1.56mg / 1 tablet
Manufacturer / importer
Genewon Sciences Co., Ltd.
Appearance
White round tablets
Packaging
30 tablets/PTP [10 tablets/PTP*3], 30 tablets/bottle
Approval status
Active

MFDS item code 201907465 · Approved 2019.10.27

Summary

Main use
Treatment of idiopathic Parkinson's disease
Who takes it
Adults
Adult dose
This medicine is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If well tolerated and an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Ingredients

Manufacturer
Genewon Sciences Co., Ltd.

Efficacy & effects

Treatment of idiopathic Parkinson's disease

  • Idiopathic Parkinson's disease
  • motor dyskinesia symptoms
View approved original text

This medication is used for the treatment of idiopathic Parkinson's disease. Initially, it can be administered alone or used as an adjunct therapy with dopamine agonists to alleviate symptoms. Additionally, for patients with motor dyskinesia, which occurs at the end of the medication's effect, it may be prescribed as an adjunct with levodopa to control symptoms. This therapeutic approach helps improve the motor function of the patient.

How to take

Adult dose

This medicine is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended initial dose for patients taking levodopa is 0.5mg once daily. If well tolerated and an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Precautions

This medication should not be administered to patients who are allergic to the active ingredient or any other components. Patients currently taking or who have stopped other MAO inhibitors or herbal medicines within the last two weeks should not use this medication. Patients currently taking or who have stopped certain medications such as meperidine, tramadol, and dextromethorphan within the last two weeks should also refrain from using this medication. Patients with moderate to severe liver impairment should not take this medication, and those with mild liver impairment should use it cautiously. During the use of this medication, various adverse reactions such as headache, dizziness, nausea, insomnia, arthralgia, skin rash, appetite loss, hallucinations, and depression may occur, and if symptoms are severe, consultation with a physician is advised. Particularly in Parkinson's disease patients, hallucinations, confusion, increased blood pressure, impulse control disorders, drowsiness, and sudden sleep attacks may occur, necessitating caution. This medication may cause serious side effects when used in combination with other antidepressants, sympathomimetics, or certain analgesics, so consultation with a doctor or pharmacist is essential. Women who are pregnant or breastfeeding should be cautious when using this medication, and its safety in children has not been established. This medication may affect the ability to drive or operate machinery; therefore, if drowsiness or sudden sleep attacks occur, such activities should be avoided. In case of overdose, dangerous symptoms such as severe hypertension or serotonin syndrome may occur, so the prescribed dosage must be strictly followed. This medication should be stored out of the reach of children and kept in a sealed container to prevent air and moisture ingress, ideally in a cool place at a temperature between 1°C and 25°C.

Side effects

  • Influenza
  • skin cancer
  • leukopenia
  • allergy
  • decreased appetite
  • depression
  • hallucination
  • headache
  • cerebrovascular accident
  • conjunctivitis
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  • dizziness
  • angina
  • myocardial infarction
  • rhinitis
  • abdominal distension
  • dermatitis
  • vesicular rash
  • musculoskeletal pain
  • neck pain
  • arthritis
  • urgency
  • fever
  • fatigue
  • peripheral edema
  • falls
  • arthralgia
  • low back pain
  • cough
  • insomnia
  • upper respiratory tract infection
  • nausea
  • constipation
  • vomiting
  • dry mouth
  • diarrhea
  • abdominal pain
  • indigestion
  • hernia
  • infection
  • gingivitis
  • accidental injury
  • weight loss
  • tendinitis
  • movement disorders
  • drowsiness
  • sensory disturbances
  • ataxia
  • muscle tone abnormalities
  • myasthenia
  • poor appetite
  • abnormal dreams
  • respiratory distress
  • rash
  • hyperhidrosis
  • orthostatic hypotension
  • petechiae
  • hemorrhage
  • melanoma
  • confusion
  • carpal tunnel syndrome
  • balance disorders
  • hallucination
  • hypertension
  • pathological gambling
  • increased libido
  • hypersexuality
  • compulsive buying or spending
  • binge eating
  • compulsive eating
  • hypotension
  • excessive drowsiness
  • acute renal failure
  • spinal fracture
  • rib fracture
  • tendon injury
  • pelvic fracture
  • leg fracture
  • upper extremity fracture
  • low back pain
  • knee joint replacement
  • herniated disc
  • hypoglycemia
  • weight loss
  • urinary retention
  • malignant hyperthermia
  • general weakness
  • pulmonary tuberculosis
  • hallucination
  • semicoma
  • gait disturbance
  • ocular motor seizure
  • facial paralysis
  • spinal canal stenosis
  • exacerbation of Parkinson's disease
  • subdural hematoma
  • pneumonia
  • myalgia
  • osteoporosis
  • limb weakness
  • unspecified laceration
  • torn wound
  • scoliosis
  • thirst
  • hematuria
  • frequent urination
  • vaginitis
  • conjunctival injection
  • diplopia
  • visual impairment
  • skin thickening
  • palpitations
  • arrhythmia
  • gastrointestinal discomfort
  • gas reflux
  • excessive salivation
  • irritable bowel syndrome
  • fissured tongue
  • increased bowel movements
  • unspecified gastrointestinal disease
  • esophagitis
  • hyperacidity
  • gastroesophageal reflux
  • gastric irritation
  • gastroenteritis
  • intestinal motility disorder
  • periodontitis
  • Helicobacter pylori gastritis
  • anemia
  • leg pain
  • chest pain
  • syncope
  • periorbital edema
  • facial flushing
  • pain
  • hallucination
  • sleep disturbance
  • aggressiveness
  • amnesia
  • memory impairment
  • lethargy
  • sleep talking
  • psychogenic sexual disorders
  • skin tingling
  • tremors
  • freezing phenomena
  • limb tremors
  • generalized muscle spasticity
  • leg cramps
  • polyuria
  • tremors
  • stuttering
  • vocal disability
  • vocal cord paralysis
  • language disorders
  • localized inflammation
  • pruritus
  • urticaria
  • eyelid skin disease
  • boil
  • hair loss
  • contusion
  • abnormal sputum
  • increased sputum
  • cold
  • bronchitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air and moisture ingress, ideally kept in a cool place at a temperature between 1°C and 25°C. Storing this way will help maintain the effectiveness of the medication for a longer period.

Appearance and packaging

Appearance

White round tablets

Package unit

30 tablets/PTP [10 tablets/PTP*3], 30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.