Alphamedipine Tablets (Amlodipine Besilate)

Adult dose

Administer 5 mg orally once daily as amlodipine, and it may be increased to a maximum of 10 mg per day based on patient response. Age and symptoms should be considered for appropriate adjustments.

This medication should not be used in certain patients. For example, patients with a history of allergies to this drug or similar drugs, nursing women, patients with severe liver dysfunction, severe aortic stenosis, and those in shock should not take this medicine. In addition, patients with severe hypotension, those requiring dialysis due to renal failure, elderly patients, and women who are pregnant or may become pregnant should use this medication with caution. When taking this medication, side effects such as facial flushing, fatigue, swelling, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea may occur. Rarely, various adverse reactions have been reported, including hypotension, vasculitis, neurological symptoms, erectile dysfunction, gynecomastia, digestive issues, weight changes, decreased blood cell counts, insomnia, and skin rash. Patients with heart failure or impaired liver function should be especially cautious while using this medication, as it may persist in the body, prolonging the blood pressure-lowering effects, so careful monitoring should continue even after discontinuation. This medication may interact with other drugs, so it is advisable to avoid taking it with grapefruit juice. Additionally, caution is needed when used in conjunction with certain antibiotics or immunosuppressants, and consultation with healthcare providers is recommended when using it with other blood pressure medications. Women who are pregnant or nursing are advised to consider alternative safe medications, as the safety of this drug has not been established, and it is recommended to discontinue breastfeeding when taking this medication. For children aged 6 and older, this medication is effective in lowering blood pressure, but its efficacy has not been confirmed in children under 6 years of age. In case of overdose, severe hypotension and tachycardia may occur, necessitating immediate medical attention, as this medication is not removed by hemodialysis and other treatment methods will be required. It is reported that this drug has little impact on driving or operating machinery, but caution is advised in cases of dizziness or drowsiness.

Serious side effects

• Hives
• angioedema
• toxic epidermal necrolysis
• jaundice
• hepatitis
• difficulty breathing
• respiratory distress
• pulmonary edema
• severe swelling

Mild side effects

• Flushing
• fatigue
• swelling
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly sealed container to protect it from air and moisture, at room temperature between 1 to 30 degrees Celsius. This helps maintain the effectiveness and safety of the medication.

Appearance

White octagonal tablet

Package unit

30 tablets - 30 tablets/bottle, 300 tablets - 300 tablets/bottle