Donepezil 5 mg (Donepezil Hydrochloride Hydrate)

Adult dose

As Donepezil Hydrochloride, it is administered at a dose of 5 mg once daily before bedtime. If unusual dreams, nightmares, or insomnia occur, morning dosing may be considered. For 4 to 6 weeks, the 5 mg dosage is administered while evaluating the clinical response, and it can be increased to 10 mg. When increasing to 10 mg daily, care should be taken regarding gastrointestinal adverse reactions during administration.

Child dose

There is no experience with usage in pediatric patients.

This medication contains Donepezil Hydrochloride Hydrate as its main ingredient and is primarily used for the treatment of symptoms of Alzheimer's type dementia. This medication should not be used in certain patients. For example, it should not be administered to individuals who are allergic to this medication or its components, pregnant women or those who may become pregnant, and patients with lactose intolerance or certain genetic metabolic disorders. Patients with heart disease or cardiac conduction disorders, those with a history of peptic ulcers or currently taking non-steroidal anti-inflammatory drugs, patients with a history of asthma or obstructive pulmonary disease, and patients with extrapyramidal disorders such as Parkinson's disease should use this medication with caution. This medication can cause various serious side effects such as bradycardia or arrhythmias, exacerbation of peptic ulcers, liver dysfunction, seizures, muscle symptoms, etc., and if these symptoms occur, one should immediately consult a physician. Additionally, various side effects such as dizziness, nausea, vomiting, diarrhea, insomnia, hallucinations, anxiety, myalgia, rash, etc., have been reported; if symptoms persist or worsen, inform healthcare personnel. This medication is not approved for other forms of dementia or memory disorders other than Alzheimer's disease, and a diagnosis and treatment should be obtained from a specialist before using it. Patients with heart-related diseases should have their heart conditions monitored periodically through electrocardiograms while taking this medication, and those with a history of peptic ulcers should carefully observe their gastrointestinal condition. Caution is needed while taking this medication, as it may affect driving or operating machinery. It is safer for pregnant or breastfeeding women not to use this medication; if necessary, consultation with a specialist is required before administration. Safety for children has not yet been established, so this medication is not used in pediatric patients. This medication may interact with other drugs, so especially when taking it alongside heart medication, antidepressants, antibiotics, anti-inflammatory drugs, etc., one must consult with healthcare personnel. In cases of overdose, severe nausea, vomiting, bradycardia, respiratory depression, etc., may occur; if these symptoms appear, immediate emergency treatment should be sought, and atropine may be used as an antidote. This medication should be kept out of reach of children and should not be transferred to another container to maintain its quality.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory distress accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizure, confusion of consciousness, vision disturbances, paralysis, urination

Mild side effects

• Nausea
• vomiting
• loss of appetite
• headache
• fatigue
• diarrhea
• insomnia
• dizziness
• drowsiness
• rash

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is best to maintain a storage temperature between 1°C and 30°C at room temperature. This will help retain the medication's effectiveness for a long time.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle