ActoZone Met Tablets 15/850 mg

Adult dosage

The dosage of this medication should be individualized based on the efficacy and tolerability, not exceeding the maximum doses for each active ingredient, which are 30 mg of Pioglitazone and 2500 mg of Metformin. The initial dose should be based on the patient's current treatment regimen, starting with one tablet daily for patients receiving monotherapy with Metformin or Pioglitazone, evaluating therapeutic response and gradually adjusting the dosage. For patients switching from combination therapy of Pioglitazone and Metformin,

This medication assists in controlling blood sugar levels. It can cause a rare but severe condition known as lactic acidosis, so patients with impaired kidney function or heart disease should exercise particular caution. Additionally, patients with impaired liver function or those who consume excessive alcohol should avoid this medication, as it may pose risks. This medication can exacerbate heart issues such as congestive heart failure, so individuals with symptoms of heart failure or severe heart conditions should not use it. If there is a history of bladder cancer or symptoms related to the bladder (such as hematuria or urinary dysfunction), immediate consultation with a physician is necessary, and bladder cancer patients should refrain from taking this medication. For patients with diminished kidney function or at risk of acute kidney failure, administration of this medication should be discontinued or used cautiously, with regular kidney function tests required. This medication may cause hypoglycemia, particularly when taken with other blood sugar-lowering agents, so careful monitoring of blood sugar changes is advised. If undergoing surgery or receiving testing involving contrast agents, temporarily discontinue this medication and resume only after confirming normal kidney function. Pregnant or nursing women should not take this medication, and safety in pediatric patients has not been established. Elderly patients have a higher risk of worsened kidney function, thus dosage should be adjusted carefully and kidney function should be monitored regularly. While taking this medication, maintain regular meals and appropriate exercise, and have regular blood sugar and blood tests done. In the event of an overdose, seek immediate medical assistance, and blood dialysis may be necessary.

Serious side effects

Severe lactic acidosis, hypoglycemia, symptoms of heart failure and congestive heart failure, severe edema, urinary abnormalities, cardiac abnormalities, severe liver failure, jaundice, severe allergic reactions, serious neurological symptoms, acute kidney function decline, kidney failure, bladder cancer, severe dermatological reactions, high fever with severe rashes and blisters, oral/ocular mucosal pain, breathing difficulties, asthma attacks, seizures, confusion, vision disturbances, paralysis, decreased urine output.

Mild side effects

• Upper respiratory infection
• diarrhea
• nausea
• headache
• urinary tract infection
• sinusitis
• dizziness
• lower limb edema
• weight gain
• anemia

This medication may be sensitive to air and humidity, so it must be stored in a sealed container. It's recommended to keep the storage temperature between 1 and 30 degrees Celsius to safely maintain the medication's efficacy.

Appearance

White to grayish-white oblong film-coated tablets

Package unit

30 tablets/PPT[(10 tablets/PTP x 3)]