Medication info
Gilect 0.5 mg (Rasagiline Mesylate)

Gilect 0.5 mg (Rasagiline Mesylate)

Prescription medicationTabletOral
Ingredient · strength
Rasagiline Mesylate›0.78mg / 1 tablet
Manufacturer / importer
Sam-il Pharmaceutical Co., Ltd.
Appearance
White or nearly white round tablets
Packaging
30 tablets/box [(10 tablets/PTP X 3)]
Approval status
Active

MFDS item code 201907386 · Approved 2019.10.22 · Insurance code 643903730

Summary

Main use
Treatment of idiopathic Parkinson's disease
Who takes it
Adults
Adult dose
This medicine is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended starting dose for patients taking levodopa is 0.5mg once daily. If well tolerated but an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Ingredients

Manufacturer
Sam-il Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of idiopathic Parkinson's disease

  • Idiopathic Parkinson's disease
  • motor fluctuation symptoms
View approved original text

This medication is used in patients with idiopathic Parkinson's disease. Initially, it can be used alone or as an adjunct to dopamine agonists to relieve symptoms. It is also administered as an adjunct during levodopa therapy when motor fluctuations occur, assisting in managing symptoms. This effectively improves motor function decline associated with Parkinson's disease.

How to take

Adult dose

This medicine is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended starting dose for patients taking levodopa is 0.5mg once daily. If well tolerated but an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Precautions

This medication should not be used by patients allergic to any of its ingredients. It should also not be administered to those currently taking or who have recently stopped taking other MAO inhibitors or certain analgesics and cough suppressants. It is not safe to use this medication in patients with moderate or severe liver dysfunction. Care should be taken as various side effects such as cold, headache, depression, dizziness, skin rash, etc., may appear while taking this medication. Especially in Parkinson's disease patients, mental symptoms such as hallucinations or confusion may occur. This medication has the potential for drug interactions, so it is essential to inform healthcare professionals about any other medications being taken. Caution is advised when driving or operating machinery due to potential drowsiness or sudden sleepiness. Pregnant or nursing women should consult a physician before using this medication. It is recommended not to use this medication in children or adolescents under 18 years of age as safety and effectiveness have not been established. Severe side effects may occur in the case of an overdose, so it is essential to adhere to the prescribed dosage and regimen. This medication should be stored out of reach of children and kept at an appropriate temperature.

Side effects

  • influenza
  • skin cancer
  • leukopenia
  • allergy
  • loss of appetite
  • depression
  • hallucination
  • headache
  • cerebrovascular accident
  • conjunctivitis
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  • dizziness
  • angina
  • myocardial infarction
  • rhinitis
  • abdominal distension
  • dermatitis
  • vesicular rash
  • musculoskeletal pain
  • cervical pain
  • arthritis
  • urinary urgency
  • fever
  • fatigue
  • nausea
  • peripheral edema
  • falling
  • arthralgia
  • low back pain
  • cough
  • insomnia
  • upper respiratory infection
  • orthostatic hypotension
  • constipation
  • vomiting
  • dry mouth
  • diarrhea
  • abdominal pain
  • dyspepsia
  • hernia
  • infection
  • gingivitis
  • traumatic injury
  • weight loss
  • tendinitis
  • dyskinesia
  • drowsiness
  • sensory disturbance
  • ataxia
  • muscle tone abnormality
  • myasthenia gravis
  • appetite loss
  • abnormal dreams
  • respiratory distress
  • rash
  • hyperhidrosis
  • petechiae
  • melanoma
  • confusion
  • carpal tunnel syndrome
  • balance disorder
  • hallucination
  • hypertension
  • pathological gambling
  • increased libido
  • hypersexuality
  • compulsive buying or shopping
  • binge eating
  • compulsive eating
  • hypotension
  • excessive drowsiness
  • acute renal failure
  • spinal fracture
  • rib fracture
  • tendon injury
  • pelvic fracture
  • leg fracture
  • upper extremity fracture
  • back pain
  • knee arthroplasty
  • disc herniation
  • hypoglycemia
  • weight loss
  • urinary difficulty
  • malignant hyperthermia
  • systemic weakness
  • pulmonary tuberculosis
  • semi-coma
  • gait disturbance
  • ocular movement seizures
  • facial paralysis
  • spinal stenosis
  • exacerbation of Parkinson's disease
  • subdural hematoma
  • pneumonia
  • myalgia
  • osteoporosis
  • limb weakness
  • concussion
  • unspecified abrasions
  • lacerations
  • scoliosis
  • thirst
  • hematuria
  • frequency of urination
  • nocturia
  • incontinence
  • vaginitis
  • conjunctival injection
  • diplopia
  • visual impairment
  • skin hypertrophy
  • palpitations
  • arrhythmia
  • gastrointestinal discomfort
  • gas reflux
  • excessive salivation
  • irritable bowel syndrome
  • fissured tongue
  • increased bowel frequency
  • unspecified gastrointestinal disease
  • esophagitis
  • hyperacidity
  • gastroesophageal reflux
  • gastric irritation
  • gastritis
  • gastrointestinal motility disorder
  • periodontitis
  • Helicobacter pylori gastritis
  • anemia
  • leg pain
  • chest pain
  • syncope
  • periorbital edema
  • facial flushing
  • pain
  • delirium
  • sleep disorder
  • aggression
  • amnesia
  • memory impairment
  • lethargy
  • sleep talking
  • psychosomatic disorder
  • skin tingling
  • tremor
  • freezing phenomenon
  • limb tremor
  • periodic limb movement disorder
  • leg cramps
  • polyuria
  • tremor
  • stuttering
  • voice disorder
  • vocal cord paralysis
  • speech disorder
  • localized inflammation
  • pruritus
  • urticaria
  • abscess
  • hair loss
  • contusion
  • abnormal sputum
  • increased sputum
  • cold
  • bronchitis
  • heartburn
  • systemic weakness
  • fatigue
  • worsened tremor

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to protect it from air and moisture. The appropriate storage temperature is a cool place between 1 and 25 degrees Celsius.

Appearance and packaging

Appearance

White or nearly white round tablets

Package unit

30 tablets/box [(10 tablets/PTP X 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.