Medication info
Rasarin Tablet 1 mg (Rasagiline Mesylate)

Rasarin Tablet 1 mg (Rasagiline Mesylate)

Prescription medicationTabletOral
Ingredient · strength
Rasagiline Mesylate›1.56mg / 1 tablet
Manufacturer / importer
Myungin Pharmaceutical Co., Ltd.
Appearance
White round tablet with 'MI' engraved on one side and a score line on the other side.
Packaging
30 tablets per bottle
Approval status
Active

MFDS item code 201907384 · Approved 2019.10.22 · Insurance code 651904860

Summary

Main use
Treatment of idiopathic Parkinson's disease
Who takes it
Adults
Adult dose
This medicine is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended starting dose for patients taking levodopa is 0.5mg once daily. If well tolerated but an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Ingredients

Manufacturer
Myungin Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of idiopathic Parkinson's disease

  • Idiopathic Parkinson's disease
  • motor fluctuations
View approved original text

This medication is used for the treatment of idiopathic Parkinson's disease. It is initially given as monotherapy or as an adjunct to dopamine agonists to help improve symptoms. Additionally, it is used as an adjunct therapy for patients experiencing motor fluctuations, particularly those with end-of-dose wearing-off effects after taking levodopa. This helps to manage Parkinson's symptoms more effectively and improve the patient's daily life.

How to take

Adult dose

This medicine is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended starting dose for patients taking levodopa is 0.5mg once daily. If well tolerated but an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Precautions

This medication should not be used in certain patients. For example, individuals who have an allergy to this drug's active ingredient or other components should not take it. Additionally, patients currently taking other MAO inhibitors or who have stopped taking them within the last two weeks should not use this medication. Patients taking specific drugs such as pethidine, tramadol, or dextromethorphan should also avoid combining them with this medication. Patients with moderate to severe liver dysfunction should not take this medication. Taking this medication may result in various side effects. The most common side effects include headache, dizziness, nausea, joint pain, insomnia, and fever. Additionally, psychiatric symptoms such as hallucinations or depression may occur, so caution is needed. This drug is used for the treatment of Parkinson's disease, and side effects such as movement disorders or decreased blood pressure have been reported. This medication may interact with other drugs, particularly other MAO inhibitors, antidepressants, sympathomimetics, and pethidine, and should not be taken with them. Furthermore, if there are any other medications being taken alongside this drug, it is essential to inform the healthcare provider or pharmacist, and not to discontinue or alter the medications without consultation. Special caution is required when taking this medication if pregnant or breastfeeding, and it should be used only after consulting a physician. The safety and efficacy of this drug have not been established in children under 18 years of age, while elderly individuals over 65 can take it without special dosage adjustments. In case of overdose, serious side effects may occur, so the prescribed dosage must be strictly followed, and if overdose is suspected, the patient should seek medical attention immediately. Lastly, this medication should be stored out of the reach of children, and the storage temperature should be maintained between 1 degree and 25 degrees Celsius, avoiding transferring it to another container.

Side effects

  • Influenza
  • skin cancer
  • leukopenia
  • allergy
  • decreased appetite
  • depression
  • hallucination
  • headache
  • cerebrovascular accident
  • conjunctivitis
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  • dizziness
  • angina
  • myocardial infarction
  • rhinitis
  • abdominal distension
  • dermatitis
  • vesicular rash
  • musculoskeletal pain
  • cervical pain
  • arthritis
  • urgency
  • fever
  • fatigue
  • peripheral edema
  • falls
  • arthralgia
  • back pain
  • cough
  • insomnia
  • upper respiratory infection
  • orthostatic hypotension
  • nausea
  • constipation
  • vomiting
  • dry mouth
  • diarrhea
  • abdominal pain
  • dyspepsia
  • hernia
  • infection
  • gingivitis
  • accidental injury
  • weight loss
  • tendinitis
  • movement disorders
  • drowsiness
  • sensory disturbances
  • ataxia
  • muscle tone abnormalities
  • myasthenia
  • loss of appetite
  • abnormal dreams
  • breathing difficulties
  • rash
  • hyperhidrosis
  • hemorrhagic spots
  • melanoma
  • confusion
  • carpal tunnel syndrome
  • balance disorders
  • hypotension
  • hypertension
  • pathological gambling
  • increased libido
  • hypersexuality
  • compulsive buying or spending
  • binge eating
  • compulsive eating
  • impulse control disorder
  • excessive drowsiness
  • acute renal failure
  • spinal fractures
  • rib fractures
  • tendon damage
  • pelvic fractures
  • leg fractures
  • upper limb fractures
  • low back pain
  • knee arthroplasty
  • herniated disc
  • hypoglycemia
  • weight loss
  • dysuria
  • malignant hyperthermia
  • general weakness
  • pulmonary tuberculosis
  • hallucination
  • semi-coma
  • gait disturbances
  • ocular dyskinesia
  • facial paralysis
  • spinal stenosis
  • exacerbation of Parkinson's disease
  • subdural hematoma
  • pneumonia
  • myalgia
  • osteoporosis
  • limb weakness
  • thirst
  • hematuria
  • frequent urination
  • vaginitis
  • conjunctival injection
  • diplopia
  • visual impairment
  • skin thickening
  • palpitations
  • arrhythmia
  • gastrointestinal discomfort
  • gas reflux
  • excessive salivation
  • irritable bowel syndrome
  • fissured tongue
  • increased bowel movement frequency
  • esophagitis
  • excessive gastric acid
  • gastroesophageal reflux
  • gastric irritation
  • gastritis
  • bowel motility disorders
  • periodontitis
  • Helicobacter pylori gastritis
  • anemia
  • leg pain
  • chest pain
  • syncope
  • periorbital edema
  • facial flushing
  • pain
  • delusion
  • sleep disorders
  • aggression
  • amnesia
  • memory impairment
  • lethargy
  • sleep talking
  • psychosexual disorder
  • skin paresthesia
  • tremors
  • freezing phenomenon
  • limb shaking
  • idiopathic muscle cramps
  • leg cramps
  • polyuria
  • shaking
  • stuttering
  • voice disorders
  • speech disorders
  • itching
  • urticaria
  • boil
  • hair loss
  • bruise
  • abnormal phlegm
  • increased phlegm
  • cold
  • bronchitis
  • chest burning
  • general weakness
  • fatigue
  • worsened tremors
  • mild hypomania
  • hypertensive crisis
  • serotonin syndrome

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is recommended to maintain the storage temperature between 1 degree and 25 degrees Celsius at room temperature. This will help to maintain the medication's effectiveness and safety.

Appearance and packaging

Appearance

White round tablet with 'MI' engraved on one side and a score line on the other side.

Package unit

30 tablets per bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.