Medication info

Rasagiline Tablets (Rasagiline Mesylate)

Prescription medicationTabletOralExpired
Ingredient · strength
Rasagiline Mesylate›1.56mg / 1 tablet
Manufacturer / importer
Korea Pharma Co., Ltd.
Appearance
White or nearly white, flat round tablets with edges
Packaging
For domestic use - 30 tablets/bottle, For domestic use - 100 tablets/bottle
Approval status
Expired

MFDS item code 201907383 · Approved 2019.10.22

This product's status changed to Expired on 2024.10.22. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Monotherapy or adjunctive treatment of idiopathic Parkinson's disease
Who takes it
Adults
Adult dose
Administer orally once daily to adults as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended starting dose for patients taking levodopa is 0.5mg once daily. If well tolerated but an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Ingredients

Manufacturer
Korea Pharma Co., Ltd.

Efficacy & effects

Monotherapy or adjunctive treatment of idiopathic Parkinson's disease

  • Idiopathic Parkinson's disease
  • motor fluctuation symptoms
View approved original text

This medication is used to treat idiopathic Parkinson's disease. In the early stages, it can be used as monotherapy or as an adjunct to dopamine agonists to manage symptoms. Additionally, in patients experiencing motor fluctuations, it is used as an adjunct with levodopa to alleviate symptoms. This can improve the patient's motor function and enhance their quality of life.

How to take

Adult dose

Administer orally once daily to adults as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended starting dose for patients taking levodopa is 0.5mg once daily. If well tolerated but an adequate clinical response is not achieved, the dose may be increased to 1mg once daily. This medicine may be taken with or without food.

Precautions

This drug should not be used by individuals who are allergic to the active ingredients or other components of this drug. It should also not be taken with other MAO inhibitors or specific analgesics, cough medicines, etc., or if usage was stopped within 2 weeks. It is unsafe to administer this drug to patients with moderate or severe liver dysfunction. Various side effects such as flu, skin cancer, leukopenia, allergies, headaches, dizziness, nausea, and insomnia may occur during the use of this drug. Particularly in patients with Parkinson's disease, symptoms such as hallucinations, confusion, and movement disorders may arise, requiring caution. This drug can cause fluctuations in blood pressure or hypotension, so blood pressure should be regularly monitored. Impulse control disorders may occur, so patients and caregivers should vigilantly observe for symptoms such as obsessive behavior or pathological gambling. Patients with decreased liver or kidney function should consult a doctor before taking this medication, and patients with severe liver disease should avoid it. This drug may induce drowsiness or sudden sleep, so caution is necessary when driving or operating hazardous machinery. There are numerous drug interactions, so consultation with a doctor or pharmacist is essential when taking it with antidepressants, analgesics, cold medicines, etc. If pregnant or nursing, a thorough consultation with a specialist should be conducted before use. Serious side effects may occur in cases of overdose, so it is imperative to adhere to the prescribed method and dosage. The safety of this drug in children has not been established; therefore, it is advisable not to use it in individuals under 18 years of age. When storing, keep it in a cool place out of reach of children and do not transfer it to another container.

Side effects

  • Influenza
  • skin cancer
  • leukopenia
  • allergies
  • loss of appetite
  • depression
  • hallucinations
  • headache
  • cerebrovascular accident
  • conjunctivitis
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  • dizziness
  • angina
  • myocardial infarction
  • rhinitis
  • abdominal distension
  • dermatitis
  • vesicular rash
  • musculoskeletal pain
  • cervical pain
  • arthritis
  • urinary urgency
  • fever
  • malaise
  • peripheral edema
  • falls
  • arthralgia
  • low back pain
  • cough
  • insomnia
  • upper respiratory infection
  • nausea
  • constipation
  • vomiting
  • dry mouth
  • diarrhea
  • abdominal pain
  • indigestion
  • hernia
  • infection
  • gingivitis
  • traumatic injury
  • weight loss
  • tendinitis
  • movement disorders
  • drowsiness
  • sensory disturbances
  • ataxia
  • muscle tension disorders
  • myasthenia
  • loss of appetite
  • abnormal dreams
  • respiratory distress
  • rash
  • hyperhidrosis
  • orthostatic hypotension
  • petechiae
  • hemorrhage
  • melanoma
  • confusion
  • carpal tunnel syndrome
  • balance disorders
  • hypotension
  • pathological gambling
  • increased libido
  • hypersexuality
  • compulsive buying or shopping
  • binge eating
  • compulsive eating
  • excessive sleepiness
  • acute renal failure
  • malignant hyperthermia
  • general weakness
  • pulmonary tuberculosis
  • hallucinations
  • semicoma
  • gait disorders
  • ocular movement seizures
  • facial paralysis
  • spinal stenosis
  • exacerbation of Parkinson's disease
  • subdural hemorrhage
  • pneumonia
  • spinal fractures
  • rib fractures
  • tendon injuries
  • pelvic fractures
  • leg fractures
  • upper limb fractures
  • low back pain
  • knee arthroplasty
  • herniated disc
  • hypoglycemia
  • weight loss
  • urinary difficulties
  • orthostatic hypotension
  • hallucinations
  • semicoma
  • gait disorders
  • dizziness
  • exacerbation of Parkinson's disease
  • hematuria
  • frequent urination
  • vaginitis
  • conjunctival hyperemia
  • diplopia
  • visual impairment
  • skin hypertrophy
  • palpitations
  • arrhythmia
  • heartburn
  • general weakness
  • fatigue
  • delusions
  • sleep disorders
  • aggression
  • amnesia
  • memory impairment
  • lethargy
  • sleep talking
  • psychosexual disorders
  • skin tingling
  • tremors
  • freezing phenomenon
  • limb tremors
  • fasciculation
  • leg cramps
  • polyuria
  • tremor
  • stuttering
  • speech disorders
  • vocal cord paralysis
  • language disorders
  • localized inflammation
  • itching
  • urticaria
  • abscess
  • hair loss
  • contusion
  • sputum abnormalities
  • increased sputum
  • cold
  • bronchitis
  • pneumonia
  • chest pain
  • syncope
  • periorbital edema
  • facial flushing
  • pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. Additionally, it is best to store the drug at room temperature between 1°C and 25°C, avoiding excessively hot or cold places.

Appearance and packaging

Appearance

White or nearly white, flat round tablets with edges

Package unit

For domestic use - 30 tablets/bottle, For domestic use - 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.