Lotazin Plus Tablet

Adult dose

The standard dosage of this medication is 50 mg of losartan potassium / 12.5 mg of hydrochlorothiazide, taken once daily as 1 tablet. Doses exceeding 100 mg of losartan potassium / 25 mg of hydrochlorothiazide are not recommended. 1. Start treatment with 50 mg of losartan potassium / 12.5 mg of hydrochlorothiazide, once daily, and if blood pressure remains uncontrolled after 3 weeks, a maximum dose of 100 mg of losartan potassium can be given.

Child dose

There is no experience with the use of this product in children and adolescents; therefore, the combination of losartan-hydrochlorothiazide should not be administered to these populations.

This medicine can cause serious harm to the fetus if taken during pregnancy, particularly in the second and third trimesters; therefore, discontinuation is necessary immediately upon confirmation of pregnancy. Patients with allergies to this medicine or its components, severely impaired kidney function, severely damaged liver function, those who are pregnant or may become pregnant should not use this medicine. Patients with low blood pressure, abnormal kidney function, liver disease, gout, or electrolyte imbalance should exercise particular caution when using this medicine, as blood pressure could drop too low or kidney function could worsen; therefore, follow the doctor's instructions. During treatment with this medicine, regular checks of potassium levels in the blood and electrolyte status are necessary to ensure there are no abnormalities, and potassium supplements or potassium-containing salt substitutes should not be taken without consulting a doctor. Due to the hydrochlorothiazide component, skin may become sensitive to sunlight, so it is advised to avoid sun exposure and to inform a doctor immediately of any unusual skin changes. Caution is needed while driving or operating machinery, as dizziness or drowsiness may occur, especially during the initial stages of treatment or with dosage changes. There may be interactions with other medications; therefore, it is essential to inform your doctor or pharmacist about any current medications, especially when taken with potassium-sparing diuretics, potassium supplements, non-steroidal anti-inflammatory drugs, and lithium. The safety and efficacy of this medicine have not been confirmed in children or adolescents, so it should not be used in these populations. Elderly patients may experience side effects more frequently, necessitating regular observation and testing. In the event of overdose, hypotension or arrhythmias may occur, so it is essential to contact a medical institution immediately, as the components of this medicine are not removed by hemodialysis and special treatments may be required. This medicine should be stored out of reach of children and kept sealed in its original container.

Serious side effects

Hives, severe swelling (edema), angioedema (laryngeal/pharyngeal swelling that can cause airway obstruction, swelling of the face/lips/pharynx/tongue), chest tightness, difficulty breathing, dyspnea, acute respiratory distress syndrome (ARDS), cold sweat, pallor, severe rash with high fever, blisters, skin peeling, mucosal pain in the mouth/eyes, yellowing of skin or eyes (jaundice), extreme lethargy, renal failure, skull formation abnormalities

Mild side effects

Abdominal pain, swelling, palpitations, back pain, dizziness, cough, sinusitis, upper respiratory tract infections, fatigue, diarrhea, nausea, headache, bronchitis, pharyngitis, angioedema (including swelling of the lips and eyelids and facial rash), chest pain, facial edema, fever, orthostatic hypotension, syncope, angina, arrhythmia (atrial fibrillation, sinus bradycardia, tachycardia, ventricular tachycardia, ventricular fibrillation), hypotension, myocardial infarction, secondary AV block, loss of appetite, constipation, tremor

This medicine may be sensitive to light, so it should be stored in a tightly sealed container that blocks light. It is recommended to maintain a storage temperature between 1°C and 30°C. Proper storage will help maintain the effectiveness and safety of the medicine for a longer period.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle