Diarein Capsule 50 mg (Diazerein)

Adult dose

Adults: Administer diacerein 50∼100mg orally in 1∼2 divided doses after meals. Adjust the dose as appropriate according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily for the first 2-4 weeks is recommended, followed by 50mg twice daily.

This medication should not be used in patients with inflammatory bowel disease or those with intestinal obstruction syndrome. Patients with unexplained abdominal pain and those who are allergic to this medication or its ingredients should also not be administered this medication. Patients with liver disease or a history of liver disease, and children under 15 years of age should not use this medication. Moreover, since this medication contains lactose, patients with lactose intolerance or certain genetic metabolic disorders should not take it. Patients with a history of issues with the small intestine or colon, pregnant or breastfeeding women, and elderly individuals over 65 should use this medication with caution. This medication contains a dye called Yellow No. 5, so individuals allergic to this ingredient should exercise caution. When taking this medication, gastrointestinal symptoms such as diarrhea, abdominal pain, and gastrointestinal bleeding may occur, so caution is advised. If diarrhea becomes severe, dehydration or electrolyte imbalance may occur, and immediate consultation with a physician is necessary if such symptoms appear. There may also be allergic reactions such as itching, rash, or eczema on the skin, and there is a possibility of liver function abnormalities, so periodic checks on liver health are required. For long-term use, strictly follow the doctor's instructions, and if diarrhea occurs, stop taking it and follow medical advice. This medication can impose a burden on the liver, so if symptoms of liver damage are suspected, discontinue use immediately and consult a physician; it is also advisable to avoid alcohol consumption. This medication may hinder absorption when taken with antacids containing calcium, magnesium, or aluminum, so it should be taken at least 2 hours apart. When taken with diuretics, there may be an increased diuretic effect, leading to dehydration and hypokalemia, so caution is required. When used in conjunction with cardiac glycosides, the risk of arrhythmia may increase, so consultation with healthcare providers is essential. Pregnant or breastfeeding women are advised not to take this medication as it may affect the fetus or newborn.

Diarrhea, loose stools, abdominal pain, gastrointestinal disorders (bleeding, ulcers, and perforation), pigmentation of the rectal mucosa, dehydration, fluid and electrolyte imbalance, itching, rash, eczema, elevated serum liver enzymes

Store this medication in a tightly sealed container to protect it from air and moisture. The recommended storage temperature is between 1 and 30 degrees Celsius (room temperature).

Appearance

A hard capsule with yellowish-brown contents and a yellow upper part and light yellow lower part.

Package unit

30 capsules/bottle, 500 capsules/bottle