Medication info

Lipirole Tablet 40 mg (Atorvastatin Calcium Trihydrate)

Prescription medicationTabletExpired
Ingredient · strength
Atorvastatin Calcium Trihydrate›43.38mg / 1 tablet
Manufacturer / importer
동광제약(주)
Appearance
White oval film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Expired

MFDS item code 201907186 · Approved 2019.10.11

This product's status changed to Expired on 2024.10.11. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Reduction of the risk of myocardial infarction and stroke, improvement of hyperlipidemia
Who uses it
Adults
Adult dosage
The recommended starting dose is 10 mg of atorvastatin once daily. If a greater reduction in LDL cholesterol is required, it may be started at 20 mg or 40 mg once daily. The dosage range is 10 to 80 mg once daily, individualized based on therapeutic goals and response. Lipid levels should be analyzed 2 to 4 weeks after starting or adjusting the dose to guide further adjustments.

Ingredients

Manufacturer
동광제약(주)

Efficacy & effects

Reduction of the risk of myocardial infarction and stroke, improvement of hyperlipidemia

  • Myocardial infarction
  • stroke
  • revascularization
  • chronic stable angina
  • retinopathy
  • albuminuria
  • congestive heart failure
  • angina
  • hypercholesterolemia
  • dyslipidemia
  • abnormal beta-lipoproteinemia
  • elevated serum triglycerides
View approved original text

This medication helps reduce the risk of cardiovascular disease. In particular, it lowers the risk of myocardial infarction and stroke, as well as the risk of revascularization and angina. Additionally, in patients with type 2 diabetes who have risk factors for coronary heart disease, this medication is effective in reducing the occurrence of cardiovascular complications. For patients already diagnosed with cardiovascular disease, it reduces the risk of hospitalization due to myocardial infarction, stroke, angina, and congestive heart failure. Furthermore, it is used to improve cardiovascular health by controlling cholesterol and triglyceride levels in patients with hyperlipidemia. In summary, this medication is used for the prevention of cardiovascular disease and the treatment of hyperlipidemia.

Dosage and Administration

Adult dosage

The recommended starting dose is 10 mg of atorvastatin once daily. If a greater reduction in LDL cholesterol is required, it may be started at 20 mg or 40 mg once daily. The dosage range is 10 to 80 mg once daily, individualized based on therapeutic goals and response. Lipid levels should be analyzed 2 to 4 weeks after starting or adjusting the dose to guide further adjustments.

Precautions

This medication may cause muscle-related symptoms, so treatment should be discontinued immediately if there is severe muscle pain or weakness, or if creatine kinase levels rise significantly. Patients at high risk of myopathy or rhabdomyolysis, such as those with serious infections, liver disease, or renal impairment, should temporarily discontinue or use the medication cautiously. It should not be used in patients with hypersensitivity to the drug, active liver disease, myopathy, pregnant or potentially pregnant women, children under the age of 10, or in combination with certain medications. Patients with impaired liver function, alcoholics, and the elderly should be closely monitored for liver and muscle conditions while using this medication, and if abnormal symptoms occur, they should consult a physician immediately. This medication can cause various side effects such as liver dysfunction, gastrointestinal disturbances, headache, muscle pain, and skin rashes, so if symptoms persist or worsen, the healthcare provider should be notified. Additionally, this medication may interact with other drugs, so if the patient is taking any other medications, this should be reported to the healthcare provider, especially when taking certain antibiotics, antifungals, antivirals, antihypertensives, or antidiabetic medications. Pregnant or breastfeeding women should not use this medication, and fertile women should use appropriate contraception while taking it. Safety in children and adolescents has not been adequately studied, so caution should be exercised in individuals under 18 years of age. There is no specific antidote for overdose; treatment should be symptomatic, and liver function and muscle enzyme levels should be monitored. The medication should be stored out of reach of children and kept in its original container. If symptoms such as muscle pain, weakness, fever, or fatigue occur while taking this medication, the patient should inform a physician immediately and undergo examination.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin shedding, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, cough accompanied by fever and respiratory abnormalities, yellowing of the skin or eyes (jaundice), profound lethargy, sudden and severe headaches, thunderclap headache, seizures, altered consciousness, vision problems, paralysis, urination issues

Mild side effects

  • Weakness
  • fatigue
  • chest pain
  • peripheral edema
  • tiredness
  • fever
  • nasopharyngitis
  • hyperglycemia
  • hypoglycemia
  • weight gain
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  • loss of appetite
  • constipation
  • abdominal bloating
  • dyspepsia
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • belching
  • pancreatitis
  • pharyngeal/laryngeal pain
  • nosebleeds
  • insomnia
  • nightmares
  • headache
  • dizziness
  • paresthesia
  • sensory loss
  • taste changes
  • memory loss
  • peripheral neuropathy
  • myalgia
  • arthralgia
  • limb pain
  • musculoskeletal pain
  • muscle cramps
  • articular issues

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent air from entering, and it is best stored at room temperature between 1°C and 30°C. This will help maintain the efficacy of the medication safely.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.