Entivagen 20 mg (Bazedoxifene Acetate)

Adult dose

Take 1 tablet (20 mg as bazedoxifene) once daily, regardless of meals.

This medication may increase the risk of blood clots in the bloodstream, so it is advisable not to use it in women with a history or risk factors for venous thromboembolism, such as deep vein thrombosis or pulmonary embolism. This medication is intended only for postmenopausal women and should not be administered to premenopausal women, pregnant women, or nursing mothers. Unexpected uterine bleeding may occur during the course of taking this medication, so if bleeding occurs, medical consultation is necessary. Its safety has not been established in patients with breast cancer, so its use is not recommended in this group. Individuals with allergies to this medication or its components, those with unexplained uterine bleeding, or those showing symptoms of endometrial cancer should avoid taking this medication. This medication contains lactose; therefore, individuals with lactose intolerance should not take it. Patients with high triglyceride levels or impaired kidney or liver function should be cautious when using this medication, particularly those with liver dysfunction, as its use is not recommended in such cases. Drowsiness or visual disturbances may occur while taking this medication; hence, caution is advised while driving or operating machinery, and if any visual problems arise, immediate consultation with a doctor is required. This medication has relatively few serious interactions with other drugs; however, it is advisable to consult with a physician or pharmacist, as drug concentrations may change when taken with some other medications. There is no specific antidote for overdose, so treatment should be based on symptoms. Keep out of reach of children and store in the original container to maintain the quality of the medication. This medication is not used in children, and dosage adjustment is not necessary in the elderly, although effects due to changes in liver function may occur.

Serious side effects

• Hives
• retinal vein thrombosis
• deep vein thrombosis
• superficial thrombophlebitis
• pulmonary embolism
• hypersensitivity

Mild side effects

Facial flushing, leg cramps, drowsiness, dry mouth, rash, itching, muscle cramps, peripheral edema, elevated blood triglycerides, increased alanine aminotransferase (ALT), increased aspartate aminotransferase (AST), vision impairment, blurred vision, photophobia, visual field defects, visual disturbances, dry eyes, eyelid edema, eyelid spasms, eye pain, swollen eyes

This medication should be stored in a tightly sealed container to prevent air or moisture from entering and should be kept in a cool place, ideally below 25 degrees Celsius, which is slightly cooler than room temperature.

Appearance

White or grayish-white capsule-shaped film-coated tablet

Package unit

28 tablets/[(28 tablets/PTP)]