Altitok Soft Capsule 10 mg (Alitretinoin)

Adult dose

Take 10~30mg once daily with or immediately after a meal. It is preferable to take it at the same time each day. The initial dose is 30mg of alitretinoin, which should be reduced to 10mg depending on adverse reactions. Patients with diabetes, obesity, cardiovascular risk factors, or dyslipidemia: Administer an initial dose of 10mg, which may be increased to 30mg if needed depending on tolerability and effect. Periodic monitoring of the blood lipid profile and blood glucose may be necessary during treatment with this medicine. Discontinue treatment as soon as the treatment goal of clear or almost clear hands is achieved. If hand eczema remains severe after the initial 12 weeks of treatment, discontinue treatment. Also discontinue treatment if the treatment goal has not been achieved by week 24.

This medication should not be used in women who are pregnant or may become pregnant. If pregnancy occurs while taking this medication, there is a very high risk of severe birth defects in the fetus, so effective two or more contraceptive methods must be used. Pregnancy tests must be conducted before starting this medication, and repeat pregnancy tests should be performed monthly during treatment. It is essential to strictly follow the physician's and pharmacist’s instructions regarding pregnancy prevention programs, and care should be taken to avoid becoming pregnant during treatment and for 1 month after stopping the medication. Blood triglyceride and cholesterol levels should be tested regularly, and immediate consultation with a doctor is required if any abnormalities occur. Care should be taken, especially if triglyceride levels rise significantly, as it may lead to serious problems such as acute pancreatitis. This medication can affect mental health, and if symptoms such as depression, mood changes, or suicidal thoughts occur, notify your doctor immediately. Patients with a history of mental illness should use this medication more cautiously, and their mental status should be consistently monitored during treatment. Excessive sun exposure or light treatments should be avoided, and sunscreen should be used if necessary to protect the skin. Vigorous exercise should also be avoided, and if dry eyes or visual problems occur, immediate consultation with medical personnel is necessary. This medication should not be used in patients with certain allergies, severe liver or kidney impairment, or uncontrolled hypothyroidism. Additionally, those with vitamin A toxicity or known hypersensitivity to this medication or similar medications should avoid taking it. If you are taking other medications, you must inform your doctor or pharmacist, and particularly, this medication should not be taken with tetracycline antibiotics. This medication should be taken with food or immediately after a meal, and it should not be chewed but swallowed whole with water. Store in a cool place out of direct sunlight, away from children, and do not take any expired medications. In case of overdose, symptoms such as severe headache, diarrhea, facial flushing, and increased triglycerides may occur, so if such symptoms arise, inform medical personnel immediately and receive appropriate treatment. For 30 days after an overdose, avoid sexual relations with women who may become pregnant or use condoms.

• Headache
• erythema
• flushing
• increased triglycerides
• increased cholesterol
• decreased thyroid-stimulating hormone
• decreased free T4
• anemia
• increased iron binding capacity
• decreased monocytes

This medication is sensitive to light and should be stored in a container that does not allow light in. Additionally, it is best stored at room temperature, between 1 to 30 degrees Celsius, that is neither too hot nor too cold. This will help maintain the medication's effectiveness over time.

Appearance

Brown oval soft capsule filled with a uniform yellow to yellow-green liquid

Package unit

30 capsules/box [(10 capsules/PTP x 3)]