Abipre Tablet 10/40 Milligrams

Adult dose

This medication is administered as one tablet once a day with water, regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning) if possible. The recommended doses are as follows: - 5/20 milligrams: for patients whose blood pressure is not adequately controlled by monotherapy with amlodipine 5 milligrams or olmesartan medoxomil 20 milligrams. - 10/20 milligrams: for patients whose blood pressure is not adequately controlled by olmesartan medoxomil 20 milligrams alone.

Child dose

Safety and efficacy for pediatric patients under 18 years have not been established.

This medication can cause serious harm to the fetus and newborn when taken during the second and third trimesters of pregnancy, so it must be discontinued immediately if pregnancy is confirmed. Patients who are allergic to the active ingredients or similar class drugs, pregnant women, breastfeeding women, patients with severe liver or aortic valve disease, patients with biliary obstruction, patients undergoing kidney dialysis, patients in shock, specific diabetic patients, and patients with severely impaired kidney function should not use this medication. It should be used with caution in patients with dehydration or low sodium levels, as hypotension may occur, and should be carefully administered to patients at risk of rapid blood pressure drop due to vasodilation, patients with coronary artery disease, patients with congestive heart failure, patients with weakened kidney function, and patients with impaired liver function. During use, side effects such as dizziness, headache, drowsiness, lowered blood pressure, nausea, vomiting, rash, and swelling may occur, so if symptoms are severe, consult a healthcare professional immediately. Although different from beta-blockers, this medication may interact with other blood pressure medications or specific drugs, so all medications being taken should be disclosed to the physician. During pregnancy, it may pose a risk to the fetus, so it is recommended to use safer alternative medications if planning to become pregnant or if already pregnant. If breastfeeding, as this medication can be transferred through breast milk and affect the baby, its use should be considered carefully. It is advisable not to use in children under 18 years of age, as safety and efficacy have not been established. Elderly patients may have reduced kidney and liver function, so it is recommended to start with a low dose and carefully monitor their condition. In case of overdose, severe hypotension and impaired heart function may occur, requiring immediate medical attention and continuous monitoring of blood pressure and heart status. This medication should be kept out of reach of children and stored in a cool place, avoiding direct sunlight and moisture.

Serious side effects

• Hives
• severe swelling (edema)
• difficulty breathing
• chest tightness
• severe allergic reaction
• severe skin adverse reaction
• jaundice of the skin and eyes
• liver abnormalities (jaundice)
• confusion
• seizures

Mild side effects

• Dizziness
• headache
• drowsiness
• paresthesia
• decreased perception
• nausea
• vomiting
• dyspepsia
• diarrhea
• constipation

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. It is also best to store it at room temperature between 1°C and 30°C, avoiding extremely hot or cold places.

Appearance

Reddish-brown round film-coated tablet

Package unit

30 tablets (10 tablets/PTP×3)