Celerive Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient, and it may be taken regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment with 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day onward, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This drug may increase the risk of gastric bleeding if taken by individuals who regularly consume more than three alcoholic drinks per day, so it is essential to consult a doctor or pharmacist. It may increase the risk of cardiovascular disease and should be used at the minimum effective dose for the shortest duration necessary, and in case of cardiovascular symptoms, immediate medical attention should be sought. Those with a history of ulcers or bleeding in the stomach should be cautious as this medication can increase the risk of gastric perforation or bleeding. This medication contains sulfonamide compounds, and should not be taken by individuals with allergic reactions or certain conditions, particularly pregnant or breastfeeding women should avoid using it. Patients with compromised liver or kidney function, or a history of heart failure, high blood pressure, or asthma should exercise caution while taking this medication and should have their condition regularly monitored as per their doctor's instructions. During the treatment, symptoms such as indigestion, abdominal pain, dizziness, headache, skin rash, swelling, and difficulty breathing may occur; if these symptoms arise, the doctor should be notified immediately. This medication may interact with other drugs, so individuals taking other medications must inform their doctor or pharmacist, especially if taking antihypertensives, anticoagulants, antidepressants, or antibiotics. Women who are pregnant or planning to become pregnant should consult a doctor before taking this medication as it may affect reproductive capacity. Elderly individuals are more likely to have decreased kidney and heart function, and thus require careful observation and dose adjustments when taking this medication. Long-term use of this medication should be monitored with regular blood tests and evaluations of liver and kidney functions to check for abnormalities. Dizziness or drowsiness may occur after taking this medication, so caution should be exercised while driving or operating machinery. There is no established safety and efficacy for children and adolescents under the age of 18, and its use is not recommended. In case of overdose, symptoms such as nausea, vomiting, and lethargy may occur, and immediate medical attention should be sought.

Gastrointestinal bleeding, cardiovascular thromboembolic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, delirium, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, abdominal distension, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, angioedema, alopecia, bullous dermatitis, peripheral edema, facial swelling, influenza-like illnesses, injuries, taste disorders, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, incontinence, urinary tract infections, visual disturbances, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, elevated alkaline phosphatase, weight gain, decreased appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthrosis, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various areas, muscle rigidity, decreased hematocrit, increased hemoglobin, petechial hemorrhage, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, purpura, contact dermatitis, injection site reactions, skin nodules, headache, dizziness, constipation, thirst, ulcerative stomatitis, gastritis, allergies, back pain, chest pain, hyperlipidemia, pneumonia, dyspnea, hearing loss, anaphylactic reactions, hallucinations, cerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthemous pustulosis, exfoliative dermatitis, generalized fixed drug eruption, fixed drug eruption, acute renal failure, hyponatremia, tubular-interstitial nephritis, nephrotic syndrome, micro-patch glomerulonephritis, menstrual disorders, female infertility, chest pain, lethargy, drowsiness, nausea, upper abdominal pain, fluid retention, systemic edema, facial edema, fatigue, malaise, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reactions, angioedema, urticaria, suicide, exacerbation of epilepsy, bronchial spasm, exacerbation of bronchial spasm, laryngitis, nosebleeds, vocal cord dysfunction, vesicular dermatitis, dermatitis, nail disorders, photosensitivity reactions, pruritus, erythematous rash, maculopapular rash, skin disorders, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, skin-mucosal syndrome, toxic epidermal necrolysis, acute generalized exanthemous pustulosis, exfoliative dermatitis, generalized fixed drug eruption, fixed drug eruption, acute renal failure, hyponatremia, tubular-interstitial nephritis, nephrotic syndrome, micro-patch glomerulonephritis, menstrual disorders, female infertility

This drug should be stored in a sealed container to protect it from air and moisture. It is also essential to store it between 15 to 30 degrees Celsius, avoiding extremes of cold or heat. Proper storage will help maintain the medication's effectiveness and safety.

Appearance

A white capsule filled with a white to pale yellow powder

Package unit

30 capsules/bottle, 100 capsules/bottle