Medication info
Anacox Capsule 100 mg (Celecoxib)

Anacox Capsule 100 mg (Celecoxib)

Prescription medicationHard capsuleOral
Ingredient · strength
Celecoxib›100mg / 1 capsule
Manufacturer / importer
Aju Pharmaceuticals Co., Ltd.
Appearance
A white capsule filled with a white to light yellow powder with blue stripes on the upper and lower parts.
Packaging
30 capsules/bottle, 100 capsules/bottle
Approval status
Active

MFDS item code 201906970 · Approved 2019.09.30 · Insurance code 654005560

Summary

Main use
Relief of arthritis and spondylitis (including osteoarthritis), acute pain in adults, and primary dysmenorrhea
Who takes it
Adults
Adult dose
The minimum recommended dose of this medicine should be adjusted for each patient and may be administered regardless of meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) Administer celecoxib 200 mg once daily or 100 mg per dose in 2 divided doses daily. 2. Rheumatoid arthritis Administer celecoxib 100 mg or 200 mg per dose 2 times daily. 3. Ankylosing spondylitis (AS) Administer celecoxib 200 mg once daily or 100 mg per dose in 2 divided doses daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, administer the recommended dose of 200 mg per dose 2 times daily as needed. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

Ingredients

Manufacturer
Aju Pharmaceuticals Co., Ltd.

Efficacy & effects

Relief of arthritis and spondylitis (including osteoarthritis), acute pain in adults, and primary dysmenorrhea

  • Osteoarthritis
  • degenerative arthritis
  • rheumatoid arthritis
  • ankylosing spondylitis
  • acute pain
  • primary dysmenorrhea
View approved original text

This medication is used to relieve the symptoms and signs of arthritis such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It also reduces acute pain occurring after surgery or tooth extraction in adults and provides relief from pain due to primary dysmenorrhea. It helps effectively alleviate various types of pain and inflammation.

How to take

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient and may be administered regardless of meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) Administer celecoxib 200 mg once daily or 100 mg per dose in 2 divided doses daily. 2. Rheumatoid arthritis Administer celecoxib 100 mg or 200 mg per dose 2 times daily. 3. Ankylosing spondylitis (AS) Administer celecoxib 200 mg once daily or 100 mg per dose in 2 divided doses daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea The initial recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, administer the recommended dose of 200 mg per dose 2 times daily as needed. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

Precautions

This medication should be discussed with a doctor or pharmacist if taken by individuals who regularly consume more than three alcoholic beverages a day due to the risk of gastrointestinal bleeding. It may increase the risk of cardiovascular diseases and should be used only for the minimum effective dose and duration; if cardiovascular symptoms appear, medical consultation is required immediately. Serious gastrointestinal issues such as perforation, ulcers, and bleeding can occur, so special caution is required for individuals with a history of gastrointestinal disease or the elderly, and treatment should be sought immediately if symptoms like abdominal pain, black stools, or vomiting blood occur. This medication should not be taken by individuals allergic to it or with certain medical conditions (severe liver or kidney impairment, active gastric ulcer, heart failure, etc.). Patients with weakened liver or kidney function, asthma, hypertension, or heart failure should take the medication cautiously under strict medical supervision. Regular liver and kidney function tests should be done while on this medication, and it should be stopped immediately if any unusual symptoms occur. This medication can interact with various drugs, so current medications should be disclosed to medical personnel. Pregnant women, those who may become pregnant, and nursing mothers should avoid this medication, and if planning a pregnancy, medical consultation is essential before taking this medication. Since dizziness or drowsiness may occur during use, caution is advised when driving or operating machinery. Rarely, serious skin reactions or blood abnormalities, liver dysfunctions may occur with prolonged use of this medication. Immediate consultation with healthcare professionals should be pursued if symptoms like skin rash, fever, or bleeding appear. Safety for children and adolescents has not been established, so it is recommended not to use it. Elderly patients may have reduced kidney and liver function, requiring more careful monitoring during use. In case of overdose, symptoms may include vomiting, drowsiness, and gastrointestinal bleeding, and immediate appropriate treatment should be sought at a medical institution. This medication should be kept out of reach of children and transferring it to another container may compromise its quality.

Side effects

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, dysgeusia, albuminuria, cystitis, hematuria, dysuria, pollakiuria, nephrolithiasis, urinary incontinence, urinary tract infection, visual disturbance, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, headache, migraine, neuralgia, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, allergic reactions, asthenia, chest pain, fluid retention, systemic edema, facial swelling, fatigue, malaise, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, vasculitis, thrombotic venous inflammation, deep vein thrombosis, cerebral hemorrhage, shingles, wound infection, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, mastodynia, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, increased serum sodium, increased serum potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical tension syndrome, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in the back, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, epistaxis, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic inflammation, contact dermatitis, injection site reactions, skin nodules, visual disturbance, conjunctivitis, pulmonary embolism, interstitial pneumonia, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease glomerulonephritis, female infertility, chest pain, asthenia, drowsiness, nausea, epigastric pain, gastrointestinal bleeding, hypertension, acute renal failure, respiratory depression, coma

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a sealed container to prevent air exposure, and keep it in a cool place between 15 to 30 degrees Celsius. This storage method helps maintain the efficacy of the medication for a longer time.

Appearance and packaging

Appearance

A white capsule filled with a white to light yellow powder with blue stripes on the upper and lower parts.

Package unit

30 capsules/bottle, 100 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.