Alison Soft Capsules 10mg (Alitretinoin)

Adult dose

Take 10~30mg once daily with a meal or immediately after a meal. It is preferable to take it at the same time each day. The initial dose is 30mg of alitretinoin; reduce the dose to 10mg according to adverse reactions. Patients with diabetes, obesity, cardiovascular risk factors, or dyslipidemia: The initial dose is 10mg and may be increased to 30mg if necessary, depending on tolerability and efficacy. Periodic monitoring of the blood lipid profile and blood glucose may be needed during treatment with this medicine. Discontinue treatment as soon as the treatment goal of clear or almost clear hands is achieved. Discontinue treatment if hand eczema remains severe after the initial 12 weeks of treatment, and also discontinue if the treatment goal has not been achieved by 24 weeks of treatment.

This medication must not be used by women who are pregnant or may become pregnant. It can cause serious fetal malformations, so pregnancy status must be verified before and during treatment, and effective methods of contraception must be used concurrently. Women who may become pregnant must avoid pregnancy during the use of this drug and for at least 1 month after treatment ends. If blood triglyceride levels are very high, there is a risk of acute pancreatitis, so regular tests for cholesterol and triglyceride levels are necessary, and dosing should be stopped if abnormalities are found. This drug should be prescribed by physicians experienced with systemic retinoid treatment, and patients with a history of mental illness should be closely monitored for depression or mood changes. This medication can cause dryness of the skin and lips, so moisturizers should be used, and excessive sun exposure should be avoided. If symptoms of dry eyes or changes in vision occur, consult a physician immediately. There is a risk of impaired night vision when driving or operating machinery, so caution is advised. Due to interactions with other drugs, inform your doctor or pharmacist of any medications you are taking. This medication should be taken with water with meals or immediately after meals and should not be chewed. Store in a cool place out of reach of children, avoiding direct sunlight. All related guidelines in accordance with the pregnancy prevention program must be adhered to by the doctor, pharmacist, and patient, and the medication must not be shared with others.

• Headache
• erythema
• flushing
• increased triglycerides
• elevated cholesterol
• decreased thyroid-stimulating hormone
• decreased free T4
• anemia
• increased iron binding capacity
• decreased monocytes

This medication is sensitive to light and should be stored in an opaque, tightly sealed container. It is also important to store it at room temperature, between 1 and 30 degrees Celsius, to prevent damage.

Appearance

Brown oval soft capsules containing a uniform yellow to yellow-green liquid

Package unit

30 capsules/box (10 capsules/PTP*3)