Aliderm Soft Capsule 30mg (Alitretinoin)

Adult dose

Take 10~30mg once daily with or immediately after a meal. It is preferable to take it at the same time each day. The initial dose is 30mg of alitretinoin; reduce the dose to 10mg depending on adverse reactions. Patients with diabetes, obesity, cardiovascular risk factors, or dyslipidemia: Start with an initial dose of 10mg and, if necessary, increase to 30mg depending on tolerability and effect. Periodic monitoring of blood lipid profile and blood glucose may be required during treatment with this medicine. Stop treatment as soon as the treatment goal of clear or almost clear hands is achieved. If hand eczema remains severe after the initial 12 weeks of treatment, discontinue treatment. Also discontinue treatment if the treatment goal has not been achieved by week 24.

This medication should never be taken by women who are pregnant or may become pregnant, as it can cause serious birth defects. Pregnancy tests must be conducted before and during treatment, and effective contraception methods must be consistently used. Regular pregnancy tests should be conducted before, during, and after treatment. Severe adverse effects such as acute pancreatitis may occur if blood triglyceride levels are very high, hence blood lipid levels should be checked regularly, and discontinuation should occur if issues arise. Patients with mental health issues or a history of depression should be cautious while taking this medication, and mental status should be frequently monitored, receiving appropriate treatment if necessary. This medication should not be administered to patients with liver dysfunction, severe kidney dysfunction, hypothyroidism, hypervitaminosis A, and specific allergies. Sensitivity to UV light increases during treatment, so it is recommended to avoid excessive sun exposure and use sunscreen. It is advised to avoid vigorous physical activity, and the use of artificial tears or lubricating eye ointment may help with dryness of the eyes. If there are any changes in vision during the course of taking this medication, the doctor must be notified immediately, especially as decreased night vision may occur, necessitating caution when driving or operating machinery. This medication should not be shared with others, and any remaining medication after discontinuation should be returned to the pharmacist. Additionally, during treatment, blood cholesterol and triglyceride levels should be periodically checked for any abnormalities. In case of overdose, severe headache, diarrhea, facial flushing, and increased triglycerides may occur, so immediate consultation with healthcare providers is required if these symptoms arise. This medication should be taken with a meal or right after a meal, without chewing, and swallowed with water. Finally, this medication must be stored in a cool place out of reach of children, avoiding direct sunlight, and medications past their expiration date should not be taken.

• Headache
• erythema
• flushing
• increased triglycerides
• increased cholesterol
• decreased thyroid-stimulating hormone
• decreased free T4
• anemia
• increased iron-binding capacity
• decreased monocytes

This medication should be stored in a tightly sealed container that protects it from light, and it is important to maintain a storage temperature between 1 degree and 30 degrees Celsius to preserve the medication's effectiveness for a prolonged period.

Appearance

Brownish-red oval soft capsule containing a uniform yellow to yellow-green liquid

Package unit

30 capsules/box [10 capsules/PTP x 3]