Alison Soft Capsule 30mg (Alitretinoin)

Adult dose

Take 10~30mg once daily with or immediately after a meal. It is preferable to take it at the same time each day. The initial dose is 30mg of alitretinoin, which may be reduced to 10mg depending on adverse reactions. Patients with diabetes, obesity, cardiovascular risk factors, or dyslipidemia: Administer an initial dose of 10mg, which may be increased to 30mg as needed depending on tolerability and effect. Periodic monitoring of blood lipid profile and blood glucose may be necessary during treatment with this medicine. Discontinue treatment as soon as the treatment goal of clear or almost clear hands is achieved. If hand eczema remains severe after the initial 12 weeks of treatment, discontinue treatment; also discontinue if the treatment goal has not been achieved by 24 weeks of treatment.

This medication should NEVER be used by women who are pregnant or may become pregnant, as it poses a very high risk of causing severe malformations in the fetus. During treatment and for a period of time after stopping the medication, effective contraception methods must be used. Pregnancy should be regularly tested and strictly monitored according to the doctor's instructions. If triglyceride levels in the blood are very high, serious side effects such as acute pancreatitis may occur, so it is important to periodically check blood lipid levels and discontinue the medication if abnormalities are found. This medication should be prescribed by a physician with professional experience and knowledge, particularly paying close attention to mental health conditions. If psychiatric symptoms such as depression, mood changes, or suicidal thoughts occur, consult a doctor immediately. Common side effects may include dry skin, chapped lips, headache, flushing, vision change, dyspepsia, which may be alleviated with dosage adjustment. This medication increases sensitivity to ultraviolet light, so excessive exposure to sunlight or artificial light sources should be avoided, and sunscreen should be used if necessary. Contact lens wear may become difficult, so it is advised to prepare glasses, and the use of artificial tears or lubricants is recommended to relieve dry eye symptoms. Co-administration of this medication with other retinoids or vitamin A increases the risk of side effects, so such combinations should be avoided, and it should not be taken with the specific antibiotic tetracycline. In accordance with the pregnancy prevention program, doctors, pharmacists, and patients must fully understand the risks associated with the use of this medication and adhere strictly to preventive measures. This medication should be taken with meals or immediately after meals, and should not be chewed but swallowed with water. For storage, keep in a cool, dry place away from children's reach, avoid direct sunlight, and store in the original container. If other medications are being taken during treatment, it is essential to inform the doctor or pharmacist, especially when combined with hormonal contraceptives, considering the potential risk of reduced contraceptive efficacy.

• Headache
• erythema
• flushing
• increased triglycerides
• increased cholesterol
• decreased thyroid-stimulating hormone
• decreased free T4
• anemia
• increased iron-binding capacity
• decreased monocytes

This medication is sensitive to light and should be stored in a tightly sealed container that blocks light. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

A reddish-brown oval soft capsule containing a uniform yellow to yellow-green liquid.

Package unit

30 capsules (10 capsules/PTP X 3)