Medication info

Lyrigabalin Capsule 150mg (Pregabalin)

Prescription medicationHard capsule경구Expired
Ingredient · strength
Pregabalin›150mg / 1 capsule
Manufacturer / importer
한국신텍스제약(주)
Appearance
A hard capsule with a white or slightly yellow powder inside, with a white upper and lower shell.
Packaging
30 capsules/bottle, 100 capsules/bottle
Approval status
Expired

MFDS item code 201906910 · Approved 2019.09.30

This product's status changed to Expired on 2024.09.30. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of peripheral and central neuropathic pain, adjunct for partial seizures, improvement of fibromyalgia.
Who takes it
Adults · Children
Adult dose
This medication is taken orally in two divided doses per day, regardless of food. 1. Neuropathic pain - Peripheral neuropathic pain: Starting dose is 150 mg once daily for 3 to 7 days, increasing to 300 mg once daily, with the maximum dose of 600 mg possible at 7-day intervals if needed. - Central neuropathic pain: Starting dose is 150 mg once daily, increasing to 300 mg after one week.
Child dose
Safety and efficacy data for children under 12 years of age and adolescents aged 12 to 17 are insufficient; therefore, administration is not recommended.

Ingredients

Manufacturer
한국신텍스제약(주)

Efficacy & effects

Treatment of peripheral and central neuropathic pain, adjunct for partial seizures, improvement of fibromyalgia.

  • Peripheral neuropathic pain
  • central neuropathic pain
  • partial seizures accompanied by secondary generalized symptoms
  • partial seizures without secondary generalized symptoms
  • fibromyalgia.
View approved original text

This medication is used to treat peripheral and central neuropathic pain in adult patients. It is also utilized as an adjunct in controlling partial seizures in patients with epilepsy, and is effective even in cases accompanied by secondary generalized symptoms. Additionally, it helps alleviate symptoms of chronic pain syndromes such as fibromyalgia. It is widely used for various neurological disorders and pain issues.

How to take

Adult dose

This medication is taken orally in two divided doses per day, regardless of food. 1. Neuropathic pain - Peripheral neuropathic pain: Starting dose is 150 mg once daily for 3 to 7 days, increasing to 300 mg once daily, with the maximum dose of 600 mg possible at 7-day intervals if needed. - Central neuropathic pain: Starting dose is 150 mg once daily, increasing to 300 mg after one week.

Child dose

Safety and efficacy data for children under 12 years of age and adolescents aged 12 to 17 are insufficient; therefore, administration is not recommended.

Precautions

This medication may increase the risk of suicidal thoughts or behaviors, so if mood changes or symptoms of depression appear during treatment, you should inform your healthcare provider immediately. Patients with allergies to this medication or specific hereditary conditions like lactose intolerance should not take it. Diabetes patients should be cautious as weight gain may require adjustments in blood sugar control medications. If severe allergic reactions such as angioedema occur, discontinue the medication immediately and consult a healthcare professional. Elderly patients should be particularly careful during the initiation phase of treatment due to the risk of dizziness or drowsiness, which may lead to falls or injuries. Blurred vision or changes in sight may occur; discontinue the medication if these symptoms appear. Abrupt discontinuation of this medication may lead to withdrawal symptoms such as insomnia, headache, and anxiety, so it should be tapered gradually after consulting with a healthcare provider. Due to the potential for misuse, caution is required for patients with a history of substance abuse. Patients with renal impairment may need dosage adjustments. Patients with severe heart disease should be careful when taking this medication. Caution is also advised when taking this medication with opioid analgesics, as the central nervous system depressant effects may be amplified. Patients with respiratory or neurological diseases, elderly patients, and those with renal impairment may be at increased risk for severe respiratory depression, so dosage adjustments may be necessary. During early pregnancy, there is a risk of fetal malformation, so women who are pregnant or planning to become pregnant should consult their healthcare provider before taking this medication and employ effective contraception methods. Breastfeeding women should consult with their healthcare provider regarding the use of this medication, as it can be passed to the baby through breast milk, potentially affecting the infant. Dizziness or drowsiness may occur when performing hazardous tasks such as driving or operating machinery, so caution is advised. If severe rashes, swelling, or respiratory difficulties occur, discontinue the medication immediately and notify a healthcare professional. In case of overdose, symptoms such as confusion, drowsiness, depression, or seizures may occur, and immediate emergency treatment is required. Keep this medication out of the reach of children and do not transfer it to other containers.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (including angioedema and facial swelling), chest tightness, difficulty breathing, cold sweats, pallor, severe rashes with high fever, blisters, peeling skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headaches, seizures, confusion, visual disturbances.

Mild side effects

  • Dizziness
  • drowsiness
  • confusion
  • impaired spatial orientation
  • irritability
  • depression
  • euphoria
  • decreased libido
  • insomnia
  • depersonalization
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  • abnormal sensations
  • restlessness
  • anxiety
  • mood fluctuations
  • emotional dullness
  • mood elevation
  • difficulty finding appropriate words
  • hallucinations
  • abnormal dreams
  • increased libido
  • panic attacks
  • impulsivity
  • apathy
  • ataxia
  • abnormal motor coordination
  • balance disorders
  • memory loss
  • attention deficit
  • memory impairment
  • tremors
  • speech impairment
  • abnormal sensations
  • sensory reduction.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication can be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is also recommended to store it at room temperature between 15 and 30 degrees Celsius. This helps to maintain the effectiveness of the medication for a longer period.

Appearance and packaging

Appearance

A hard capsule with a white or slightly yellow powder inside, with a white upper and lower shell.

Package unit

30 capsules/bottle, 100 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.