Enticeren Capsule 50 mg (Diacerhein)

Adult dose

Adults: Administer 50∼100mg of diacerein daily orally after meals, in 1∼2 divided doses. Adjust the dose as appropriate according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily is recommended for the first 2-4 weeks, followed by 50mg twice daily.

This medication should not be used in patients with specific diseases. For example, patients with inflammatory bowel disease or those with intestinal obstruction syndrome should not take it. Moreover, patients with unexplained abdominal pain or those allergic to this drug or its ingredients should also avoid it. Patients with liver disease or a history of liver problems, as well as children under 15 years of age, should not use this medication. Since this medication contains lactose, patients with lactose intolerance or hereditary lactose metabolism disorders should not take it. Patients with a history of small intestine or colon disease should be particularly cautious when using this drug, and pregnant or breastfeeding women should carefully consider if they should take this medication. Older adults over 65 years of age should use this medication at a reduced dosage for safety. Taking this medication may affect the digestive system, leading to symptoms such as diarrhea or abdominal pain, and long-term use may cause serious issues like gastrointestinal bleeding, ulcers, or perforation. Severe diarrhea may lead to dehydration and electrolyte imbalance, so care is needed. Skin reactions such as itching, rash, eczema, and, rarely, abnormal liver function may occur. When used for long periods, it is essential to follow a doctor’s guidance, and if diarrhea occurs, discontinue the medication and consult with a physician. It is advisable to avoid taking it alongside laxatives. Due to the risk of liver damage, caution is needed when taking this drug with other medications that may affect liver function or have hepatotoxicity, and it is advisable to limit alcohol consumption. This medication may be hindered in absorption when taken with specific antacids or salts, so a minimum 2-hour interval should be maintained between these medicines. Taking it with diuretics may increase the diuretic effect, thus presenting risks of dehydration and hypokalemia, so care is required. Additionally, taking it alongside cardiac glycosides may increase the risk of arrhythmias, hence caution is advised. Pregnant or breastfeeding women are advised against using this medication, as it may affect the fetus or newborn. In case of overdose, severe diarrhea may occur, and appropriate treatment such as electrolyte supplementation may be necessary.

diarrhea, loose stools, abdominal pain, gastrointestinal disorders (bleeding, ulcers, and perforation), pigmentation of the rectal mucosa, itching, rash, eczema, elevated liver enzymes in serum

This medication should be stored in a tightly closed container to protect it from air and humidity, preferably at room temperature between 1 to 30 degrees Celsius. Maintaining this storage will help preserve the efficacy of the drug for a longer period.

Appearance

A white hard capsule with the upper part filled with brownish-yellow contents and a yellow lower part.

Package unit

30 capsules/bottle, 500 capsules/bottle