Ostok Soft Capsule 30 mg (Alitretinoin)

Adult dose

Take 10~30mg once daily with or immediately after a meal. It is preferable to take it at the same time each day. The initial dose is 30mg of alitretinoin; reduce to 10mg according to adverse reactions. Patients with diabetes, obesity, cardiovascular risk factors, or dyslipidemia: The initial dose is 10mg; if necessary, it may be increased to 30mg according to tolerability and efficacy. Periodic monitoring of the blood lipid profile and blood glucose may be necessary during treatment with this medicine. Discontinue treatment as soon as the treatment goal of clear or almost clear hands is reached. Discontinue treatment if hand eczema remains severe after the initial 12 weeks of treatment, and also discontinue if the treatment goal has not been achieved by 24 weeks of treatment.

This medication must not be used by women who are pregnant or may become pregnant due to the very high risk of causing serious birth defects. Women of childbearing potential must undergo pregnancy testing before, during, and after treatment and must use two effective forms of contraception. If a pregnancy occurs during treatment, immediate consultation with a physician is required. Severe elevations in triglyceride levels can lead to serious side effects like acute pancreatitis; therefore, regular blood tests to check lipid levels are necessary. If lipid levels are not controlled, the use of this medication should be discontinued. It is recommended that this medication be prescribed by a specialist experienced in systemic retinoid therapy. Patients with severely decreased liver or kidney function, uncontrolled hypothyroidism, hypervitaminosis A, and those allergic to this medication or similar components should not use it. Patients with a history of mental illness or symptoms of depression must be closely monitored for their mental health status while taking this medication; if symptoms worsen, treatment should be immediately discontinued, and a physician should be consulted. While taking this medication, excessive sun exposure or the use of UV lamps should be avoided, and sunscreen should be used if necessary. Additionally, it is advisable to refrain from vigorous exercise. Dry eyes or changes in vision may occur; therefore, if dryness of the eyes develops, supplementary treatment with artificial tears may help, and any visual disturbances should be reported to a physician immediately. This medication should not be shared with others, and any leftover medication after treatment should be returned to a pharmacist. Moreover, patients who are taking or have discontinued this medication within the last month should not donate blood. Care should be taken concerning drug interactions, especially not to use it with vitamin A or other retinoid preparations, or tetracycline antibiotics. Patients taking other medications must inform their physician or pharmacist. When taking this medication, it must be swallowed with water, with or immediately after meals, and care should be taken not to chew the capsules. Store this medication at room temperature between 1 to 30 degrees Celsius, in a place that is protected from light, and in a safe location out of the reach of children.

• Headache
• erythema
• flushing
• increased triglycerides
• increased cholesterol
• decreased thyroxine-stimulating hormone
• decreased free T4
• anemia
• increased iron-binding capacity
• decreased monocytes

This medication is sensitive to light and should be stored in a specific container that does not allow light exposure. Additionally, it is best stored at room temperature between 1 to 30 degrees Celsius to maintain the effectiveness of the medication for a longer time.

Appearance

Brown-red oval soft capsules containing a uniform yellow to yellow-green liquid

Package unit

30 capsules/box [10 capsules/PTP X 3]