Glufomin Sustained Release Tablet 500mg (Metformin Hydrochloride)

Adult dose

The initial dose is 500mg of Metformin Hydrochloride sustained release tablet once a day with the evening meal. The dose should be determined based on individual drug efficacy and tolerance, and it can be administered up to a maximum of 2000mg per day with the evening meal. When increasing the dose, it should be increased by 500mg weekly, and if blood sugar is not controlled even after taking 2000mg, consider administering 1000mg twice a day with meals. For patients with renal impairment,

This medication can rarely cause a serious condition called lactic acidosis, so if these symptoms occur, immediate notification to medical personnel is required. Caution is necessary as hypoglycemia may occur when used in combination with other diabetes medications. This medication should not be used in patients with moderate to severe renal impairment or acute illness. It is also safer for patients with heart-related diseases such as heart failure or acute myocardial infarction not to take this medication. Before and after examinations using iodinated contrast agents, this medication should be discontinued due to the risk of renal function deterioration and lactic acidosis and should be resumed after a certain period. Patients who are allergic to any components of this medication or who have type 1 diabetes should not use it. This medication should also be temporarily stopped in cases of severe infections, systemic disorders, and before and after surgery. Patients with poor nutritional status, liver function impairment, and excessive alcohol intake should also use caution with this medication. This medication can cause gastrointestinal disturbances, taste alteration, vitamin B12 deficiency, and especially, digestive symptoms are commonly seen at the onset of treatment. Regularly monitor renal function to reduce the risk of accumulation and side effects of this medication, and discontinue use if renal function declines. Caution is needed due to the risk of hypoglycemia in cases of irregular meals, vigorous exercise, and combination with other medications. During pregnancy, careful consideration is required regarding the effects on the fetus, and its use during breastfeeding is not recommended. Elderly individuals may have a risk of reduced renal function; thus, dose adjustment and regular function monitoring are necessary. In cases of overdose, blood dialysis can be used to remove the drug, so inform medical personnel immediately. This medication should be swallowed whole and should not be chewed or crushed, and the tablet shell may appear in the stool, which is normal. This medication can interact with other drugs, so inform medical personnel of any other medications being taken, and regularly check blood sugar and renal function. While taking this medication, excessive alcohol consumption should be avoided, and regular monitoring of blood sugar and health status is important.

Serious side effects

• Lactic acidosis
• urticaria
• severe swelling (edema)
• difficulty breathing
• severe allergic reactions
• severe skin abnormal reactions

Mild side effects

• Vitamin B12 deficiency
• taste impairment
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• erythema
• itching
• urticaria

This medication may be sensitive to air and moisture, so it should be stored in a closed container. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius room temperature. Storing it this way helps maintain the effectiveness of the medication.

Appearance

White, double convex, oblong sustained release tablet

Package unit

30 tablets/bottle, 300 tablets/bottle