Pantaryl Tablet 20 mg (Pantoprazole Sodium Sesquihydrate)

Adult dosage

1. Treatment of mild reflux esophagitis and associated symptoms: Administer 20 mg of pantoprazole orally once daily before breakfast. Symptom relief generally occurs within 2 ∼ 4 weeks, and healing can usually be achieved with 4 weeks of treatment. If healing is not achieved, an additional 4 weeks of treatment may achieve healing. 2. Long-term maintenance therapy to prevent recurrence of reflux esophagitis: Administer 20 mg of pantoprazole once daily before breakfast. If relapse occurs, increase the dose to 40 mg of pantoprazole daily, then reduce it to 20 mg daily again after healing. 3. Prevention of gastroduodenal ulcers caused by nonsteroidal anti-inflammatory drugs in patients requiring continuous NSAID treatment: Administer 20mg of pantoprazole once daily. • No dose adjustment is necessary in older adults or patients with renal impairment. • Patients with hepatic impairment Do not exceed 20 mg of this drug once daily in patients with severe hepatic impairment.

This medication should not be given to individuals who are allergic to it or its components, or have a history of hypersensitivity. Serious allergic reactions such as anaphylaxis, angioedema, and bronchospasm may occur. Furthermore, it should not be administered to patients taking specific antiviral drugs like atazanavir and nelfinavir, pregnant women in their early stages or those who may become pregnant, breastfeeding women, and patients taking rilpivirine-containing medications. This medication can cause various side effects. Gastrointestinal side effects may include abdominal pain, constipation, abdominal bloating, diarrhea, nausea, vomiting, belching, and dry mouth. Generalized side effects may include fatigue, weakness, malaise, edema, and fever. It can affect liver function, leading to elevated liver enzyme levels or jaundice; hence, liver function tests are necessary, as severe liver damage may occur. Immunological reactions may lead to serious allergic responses like anaphylactic shock, and musculoskeletal side effects may include arthralgia and myalgia, with severe cases leading to rhabdomyolysis. Neurological side effects may present as headaches, dizziness, vision disorders, and taste abnormalities, while psychiatric symptoms reported include insomnia, depression, hallucinations, and confusion. It may also affect the kidneys and urinary tract, potentially causing acute interstitial nephritis. Dermatological reactions may consist of pruritus, urticaria, and serious skin conditions such as Stevens-Johnson syndrome. Long-term use of this medication may cause vitamin B12 absorption impairment and increase the risk of fractures; therefore, caution is required. Additionally, it suppresses gastric acid secretion, which might slightly increase the risk of infections due to increased bacteria in the stomach; if diarrhea persists, consultation with a healthcare professional is advised. Patients experiencing dizziness or vision disturbances should avoid dangerous activities such as driving or operating machinery. This medication may interact with other drugs, so it's important to inform healthcare providers, especially when taken with anticoagulants, antiviral medications, or immunosuppressants. It should not be administered during the first three months of pregnancy, and breastfeeding women should avoid its use. The use in children under 12 years is not recommended. No specific symptoms are known for overdose, but if unusual symptoms appear, healthcare professionals should be informed immediately for appropriate treatment. This medication should be taken whole without chewing or crushing, and regular check-ups are necessary for long-term administration. Keep out of reach of children and avoid transferring the medication to other containers.

Anaphylaxis, anaphylactic shock, angioedema, bronchospasm, acute interstitial nephritis, urticaria, abdominal pain, constipation, abdominal distension, diarrhea, gastric polyp, nausea, vomiting, belching, dry mouth, fatigue, asthenia, lethargy, edema, elevated body temperature, fever, increased liver enzymes, elevated bilirubin, liver failure, arthralgia, myalgia, rhabdomyolysis, bone fracture, headache, dizziness, visual disturbance, taste alteration, insomnia, sleep disorder, depression, hallucination, confusion, spatial disorientation, interstitial nephritis, pruritus, skin erythema, angioedema, mucocutaneous syndrome, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, photosensitivity, hyperglycemia, agranulocytosis, leukopenia, thrombocytopenia, pancytopenia, gynecomastia, hyperlipidemia, lipid increase, weight change, hyponatremia, hypomagnesemia, elevated CK, anxiety, apathy, low energy, back pain, bronchitis, chest pain, increased cough, dyspepsia, dyspnea, flu symptoms, gastroenteritis, gastrointestinal disorder, tension, infection, migraine, cervical pain, pain, pharyngitis, rectal disorder, rhinitis, elevated AST, sinusitis, upper respiratory infection, increased urination, urinary tract infection, boil, allergic reaction, chills, abscess, facial edema, general edema, heat sensation, hernia, abnormal clinical laboratory test results, malaise, moniliasis, tumor, nonspecific drug reaction, abnormal ECG, angina pectoris, arrhythmia, atrial fibrillation, coronary artery disease, congestive heart failure, bleeding, hypertension, hypotension, myocardial infarction, myocardial ischemia, palpitations, retinal vascular disease, syncope, tachycardia, phlebitis, thrombosis, vasodilation, decreased appetite, aphthous stomatitis, colitis, duodenitis, dysphagia, enteritis, esophageal bleeding, esophagitis, gastric and duodenal tumor, gastric and duodenal bleeding, gastric and duodenal moniliasis, gingivitis, halitosis, hematemesis, increased appetite, melena, oral ulcer, oral moniliasis, periodontal abscess, periodontitis, rectal bleeding, gastric ulcer, bowel irregularity, tongue discoloration, ulcerative colitis, diabetes, goiter, gallbladder pain, hyperbilirubinemia, cholecystitis, cholelithiasis, jaundice, hepatitis, elevated ALP, anemia, petechiae, eosinophilia, iron deficiency anemia, leukocytosis, leukopenia, thrombocytopenia, dehydration, gout, thirst, weight gain, weight loss, arthritis, bone disease, joint disease, leg cramps, bursitis, tendinitis, abnormal dream, confusion, convulsion, dry mouth, speech disorder, hyperactivity, decreased libido, restlessness, neuralgia, neuritis, neurologic disorder, dysesthesia, reduced reflexes, drowsiness, altered perception, tremor, asthma, epistaxis, hiccups, laryngitis, respiratory distress, pneumonia, voice alteration, acne, alopecia, contact dermatitis, eczema, fungal dermatitis, bleeding, herpes simplex, shingles, lichen planus dermatitis, papulovesicular rash, skin disease, skin ulcer, sweating, amblyopia, cataract, hearing loss, diplopia, ear pain, paralysis, glaucoma, otitis externa, tinnitus, albuminuria, balanitis, mastalgia, cystitis, menstrual irregularity, dysuria, epididymitis, hematuria, erectile dysfunction, nephrolithiasis, renal pain, nocturia, prostate disorder, pyelonephritis, scrotal edema, urethral pain, urethral disease, urological abnormalities, vaginitis, Clostridium difficile-associated diarrhea, hypocalcemia, hypokalemia, DRESS syndrome, microscopic colitis, systemic lupus erythematosus, erythematous lupus

This medication is sensitive to light and should be stored in a container that does not allow light to enter. It is also advisable to store it at room temperature, between 1 to 30 degrees Celsius. This will help maintain the medication’s effectiveness for a longer duration.

Appearance

Yellow enteric-coated oval tablets

Package unit

30 tablets/bottle