Palm Talk Soft Capsule 10mg (Alitretinoin)

Adult dose

Take 10~30mg once daily with or immediately after a meal. It is preferable to take it at the same time each day. The initial dose is 30mg of alitretinoin; reduce to 10mg depending on adverse reactions. Patients with diabetes, obesity, cardiovascular risk factors, or dyslipidemia: Administer an initial dose of 10mg and, depending on tolerability and efficacy, increase to 30mg if needed. Periodic monitoring of the blood lipid profile and blood glucose may be needed during treatment with this medicine. Discontinue treatment as soon as the treatment goal of clear or almost clear hands is achieved. If hand eczema remains severe after the initial 12 weeks of treatment, discontinue treatment; also discontinue treatment if the treatment goal has not been achieved by Week 24.

This medication must not be used by women who are pregnant or may become pregnant, as there is a very high risk of serious fetal malformations. Pregnancy tests must be conducted regularly before and during the use of this medication, and effective two methods of contraception must be used concurrently. Contraception should be maintained from one month before treatment starts until one month after treatment ends. Blood triglyceride and cholesterol levels should be monitored regularly, and if levels are very high or symptoms of pancreatitis occur, the medication should be discontinued immediately. Patients with mental health issues or a history of depression should use this medication with special caution, and if mood changes or symptoms of depression appear during treatment, they should consult a physician immediately. This medication should not be used in patients with poor liver or kidney function, uncontrolled thyroid dysfunction, vitamin A excess, or certain allergies. During treatment, excessive sun exposure should be avoided, sunscreen should be used, and vigorous exercise should be avoided. Also, as dryness of the eyes may occur, artificial tears or lubricating eye ointments should be used as necessary. Taking this medication concurrently with other vitamin A preparations or tetracycline antibiotics can be risky, so it is essential to inform your doctor or pharmacist about any other medications being taken. In accordance with the pregnancy prevention program, doctors and pharmacists must provide thorough guidance to patients regarding the risks of this medication and contraception, and the patient must agree and comply with this. In case of an overdose, symptoms such as severe headache, diarrhea, facial flushing, and increased triglycerides may appear, and in such cases, immediate medical attention must be sought. This medication should be taken with or just after meals, and it should be swallowed whole with sufficient water without chewing. For storage, keep this medication out of the reach of children, store it in a cool place below 30 degrees Celsius, avoiding direct sunlight, and keep it sealed in its original container.

• headache
• erythema
• flushing
• increased triglycerides
• increased cholesterol
• decreased thyroid-stimulating hormone
• decreased free T4
• anemia
• increased iron-binding capacity
• decreased monocytes

This medication may be light-sensitive, so it should be stored in a container that does not allow light to enter. Additionally, it is best stored at room temperature between 1 and 30 degrees Celsius. Storing it this way helps retain the medication's effectiveness longer.

Appearance

Brown oval soft capsules containing a uniform yellow to yellow-green liquid.

Package unit

30 capsules / box [10 capsules / PTXP x 3]