Exidazole 40 mg (Esomeprazole Magnesium Trihydrate)

Adult dosage

This medication should be swallowed with liquids such as water and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks - Maintenance therapy to prevent recurrence of esophagitis: 20 mg once daily - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: 20 mg once daily - If necessary, once daily, 1 dose

Children's dosage

Adolescents aged 12 years and older - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: 20 mg once daily - Symptoms

This medication should not be used in certain patients. For example, patients who are allergic to this medication or its components or have experienced hypersensitivity reactions to similar medications in the past should not receive this treatment. Particular caution is required for patients who are allergic to penicillin antibiotics or macrolide antibiotics when used together with this medication. Additionally, patients taking certain heart-related medications or with a history of myocardial infarction, as well as nursing women, should not use this medication. Various adverse reactions may occur while taking this medication, so symptoms should be carefully monitored. Gastrointestinal symptoms such as headache, abdominal pain, diarrhea, nausea, and vomiting can occur, as well as skin rashes, itching, and rarely severe skin reactions. Blood abnormalities, neurological issues, and electrolyte imbalances such as hypomagnesemia may also occur, necessitating regular testing. Long-term use has been reported to increase the risk of fractures, so patients with osteoporosis should use it cautiously. This medication may interact with other drugs, so if any other medications are being taken, consultation with a doctor or pharmacist is crucial. Caution is also warranted when used with antiviral drugs, antibiotics, anticoagulants, as it may change drug concentrations and increase the risk of side effects. It should be used cautiously during pregnancy due to insufficient safety confirmation, and it is advisable not to use it while breastfeeding. There is no specific antidote for overdose; appropriate treatment should be administered according to symptoms, and it should be kept out of reach of children. It is advisable to avoid transferring the medication to another container as it may lead to deterioration in quality or risk of accidents.

Serious side effects

Hives, angioedema, anaphylaxis, shock, fever, severe allergic reactions, severe skin adverse reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, eosinophilia with systemic symptoms drug reaction, microscopic colitis, jaundice, hepatitis, liver failure, encephalopathy, severe neurological symptoms (headache, seizures, confusion, visual disturbances, paralysis), severe edema accompanied by elevated blood pressure

Mild side effects

Headache, dizziness, sensory disturbances, drowsiness, taste disorders, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, increased liver enzymes, hepatitis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, muscle weakness, nephritis, gynecomastia, fatigue, increased sweating, Clostridium difficile-associated diarrhea, allergic reactions, back pain, chest pain

This medication should be stored in a tightly closed container to protect it from air or moisture, and it is recommended to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage ensures that the efficacy of the medication is maintained and prevents deterioration.

Appearance

Pink round film-coated tablet

Package unit

PTP packaging - 28 tablets/PTP [14 tablets/PTP x 2]