Uglime Metformin Tablets 15/850 mg (Pioglitazone Hydrochloride, Metformin Hydrochloride)

Adult dosage

This medication should generally be taken divided with meals to reduce gastrointestinal adverse effects caused by Metformin. The initial dose should be based on the patient's current treatment regimen, starting with one tablet daily and gradually adjusting the dose after evaluating treatment response. The dose of this medication should not exceed the maximum dosages of pioglitazone 30 mg and metformin 2500 mg for efficacy and tolerance.

This medication helps regulate blood sugar. However, it should not be used in patients with impaired kidney function or severe heart disease. In particular, this medication can cause a serious side effect called lactic acidosis, which is a dangerous condition where lactic acid accumulates excessively in the body. Lactic acidosis is very rare but can be fatal, so if symptoms such as sudden shortness of breath, muscle pain, fatigue, or abdominal pain appear, one should consult a physician immediately. Additionally, this medication should not be taken by patients with liver dysfunction or individuals who consume alcohol excessively. This medication may worsen heart failure, so caution is necessary for patients with heart failure. During treatment, it is essential to carefully monitor for symptoms of heart failure such as weight gain, swelling, or shortness of breath. This medication is not recommended for women who are pregnant or breastfeeding. Also, while using this medication, regular monitoring of blood sugar, liver function, kidney function, and blood tests is necessary. Overdosing on this medication may lead to hypoglycemia or severe side effects; therefore, it is crucial to adhere to the prescribed dosage. Before any sudden surgery or diagnostic tests using contrast agents, one should consult a physician to temporarily discontinue the medication. Additionally, there may be other medications that interact with this medication, so inform your doctor or pharmacist if you are taking any other drugs. Lastly, this medication's safety has not been established in children, and for the elderly, dosage adjustment and monitoring are required due to potential declines in kidney function.

Serious side effects

Lactic acidosis, severe edema, symptoms and signs of heart failure (including excessive and rapid weight changes, shortness of breath, swelling), hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, liver function abnormal symptoms (jaundice, yellowing of the skin or eyes), severe skin adverse reactions (severe rash with high fever, blisters, skin peeling, pain in mouth/eye mucous membranes), severe neurological symptoms (sudden and very

Mild side effects

• Upper respiratory tract infections
• diarrhea
• nausea
• headache
• urinary tract infections
• sinusitis
• dizziness
• lower limb edema
• weight gain
• muscle pain

This medication may be sensitive to air or moisture, so ensure that it is stored in a sealed container. It is best to maintain the storage temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's efficacy over time.

Appearance

White to pale gray oblong film-coated tablets

Package unit

30 tablets/PTP [(10 tablets/PTP * 3)]