Erosuvab 5 mg Tablet (Rosuvastatin Calcium (unrefined))

Adult dosage

Can be taken at any time of the day regardless of meals. The initial dose is 5 mg once daily, and the maintenance dose is 10 mg once daily. Depending on LDL-cholesterol levels, treatment goals, and the patient's response, the dosage may be appropriately adjusted at intervals of 4 weeks or more, with a maximum daily dose of 20 mg.

Children's dosage

Pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) are administered once daily with doses ranging from 5 mg to 20 mg. The dosage should be adjusted based on the individual treatment goal at intervals of 4 weeks or more.

This medication should not be administered to certain patients. For instance, patients with allergies to the ingredients of this medication, those with severely impaired liver function, those with muscle disorders, patients with significantly reduced kidney function, pregnant or breastfeeding women, and fertile women not using appropriate contraception should not take this medication. Moreover, high dosing of this medication is prohibited for patients at high risk of muscle-related side effects. Patients with risk factors such as genetic muscle disorders, hypothyroidism, or alcohol abuse should be particularly cautious. This medication contains lactose and should not be used by patients with lactose intolerance or certain genetic digestive disorders. Patients with a history of liver disease or excessive alcohol consumption should have regular liver function tests while using this medication, and patients with hyperlipidemia due to thyroid dysfunction or nephrotic syndrome must first treat the underlying cause. If symptoms such as myalgia, muscle weakness, or cramps occur, the patient should immediately inform their doctor and undergo necessary tests; in severe cases, discontinuation of the medication may be necessary. This medication may rarely cause serious skin reactions, liver damage, kidney abnormalities, and neurological symptoms in some patients, so immediate consultation with healthcare professionals is advised if such symptoms develop. Additionally, this medication may interact with several other drugs; therefore, patients should inform healthcare professionals about any other medications they are taking, especially when combined with certain antivirals, immunosuppressants, antifungals, some antibiotics, and fibrate drugs. Women who are pregnant or might become pregnant must ensure appropriate contraception and should stop taking this medication immediately if pregnancy is confirmed. In the event of overdose, as no specific antidote exists, treatment must be symptomatic, and liver function and muscle enzyme tests are necessary. This medication does not appear to significantly affect the ability to drive or operate machinery; however, caution is advised due to potential dizziness. Finally, this medication may show higher blood concentrations in Asians, thus dosage adjustments may be necessary.

Serious side effects

Urticaria, hypersensitivity reactions including angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, severe muscle weakness, rhabdomyolysis, immune-mediated necrotizing myopathy, polyneuropathy, acute renal failure, oliguria, severe edema, chest tightness, dyspnea, asthma attacks

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• fatigue
• thrombocytopenia
• diarrhea

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain a storage temperature in the range of 1 to 30 degrees Celsius. Proper storage will help maintain the efficacy and safety of the medication.

Appearance

Yellow round film-coated tablet

Package unit

Bottle - 30 tablets/bottle