Medication info

Hyubika HCT Tablet 10/40/12.5 mg

Prescription medicationTablet경구Expired
Ingredient · strength
Olmesartan Medoxomil›40mg / 1 tabletAmlodipine Besylate›13.888mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
(주)휴비스트제약
Appearance
Round film-coated tablet in reddish gray
Packaging
30 tablets/PPT [(10 tablets/Alu-Alu × 3)]
Approval status
Expired

MFDS item code 201906514 · Approved 2019.09.18

This product's status changed to Expired on 2024.09.18. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Improvement in blood pressure control for essential hypertension
Who takes it
Adults · Children
Adult dose
This drug is taken once daily, with or without food, and should be taken with water. It is recommended to take it at the same time each day (e.g., in the morning). The dosing recommendations are as follows: - 5/20/12.5 mg: Administered to patients in whom blood pressure is not adequately controlled with the combination therapy of Amlodipine/Olmesartan medoxomil 5/20 mg. - 5/40/12.5 mg: Administered to patients in whom blood pressure is not adequately controlled with the combination therapy of Amlodipine/Olmesartan medoxomil 5/40 mg.
Child dose
Safety and efficacy in pediatric patients under 18 years of age have not been established, and administration of this drug is not recommended.

Ingredients

Manufacturer
(주)휴비스트제약

Efficacy & effects

Improvement in blood pressure control for essential hypertension

  • Essential hypertension
View approved original text

The combination therapy of amlodipine and olmesartan medoxomil is used when blood pressure is not adequately controlled in patients with essential hypertension. These medications each lower blood pressure, and their combined use may enhance efficacy. Essential hypertension refers to high blood pressure that occurs without a specific cause, making blood pressure control crucial. This combination therapy helps manage blood pressure more effectively and reduces the risk of cardiovascular complications. Therefore, this drug combination is used in the treatment of essential hypertension.

How to take

Adult dose

This drug is taken once daily, with or without food, and should be taken with water. It is recommended to take it at the same time each day (e.g., in the morning). The dosing recommendations are as follows: - 5/20/12.5 mg: Administered to patients in whom blood pressure is not adequately controlled with the combination therapy of Amlodipine/Olmesartan medoxomil 5/20 mg. - 5/40/12.5 mg: Administered to patients in whom blood pressure is not adequately controlled with the combination therapy of Amlodipine/Olmesartan medoxomil 5/40 mg.

Child dose

Safety and efficacy in pediatric patients under 18 years of age have not been established, and administration of this drug is not recommended.

Precautions

This drug may cause serious harm to the fetus and newborn in the second and third trimesters of pregnancy, and should be discontinued immediately upon confirmation of pregnancy. Do not use in patients with an allergy to this drug or its components, those who are pregnant or breastfeeding, or in patients with severe hypotension or heart and kidney diseases. Patients with reduced blood volume or impaired kidney function may experience symptoms of hypotension upon initial use of this drug, so they should be carefully monitored. This drug can affect kidney function or electrolyte balance; therefore, patients with kidney disease, liver disease, electrolyte abnormalities, or heart disease should consult their doctor before use. Particularly, elderly patients, those with diabetes, gout patients, and patients with acute closed-angle glaucoma should exercise caution when taking this drug. This drug may interact with other medications, so it is essential to inform your physician of current medications, especially when taking lithium, NSAIDs, other antihypertensive agents, potassium-sparing diuretics, etc. Regular monitoring of blood pressure, kidney function, and electrolyte levels is necessary to ensure they remain within normal ranges. Common side effects include hypotension, headache, dizziness, peripheral edema, upper respiratory infection, nasopharyngitis, urinary tract infection, sialadenitis, leukopenia, thrombocytopenia, bone marrow suppression, neutropenia, agranulocytosis, hemolytic anemia, aplastic anemia, drug hypersensitivity, hyperkalemia, hypokalemia, loss of appetite, diabetes, hypercalcemia, hyperglycemia, hypomagnesemia, hyponatremia, hypochloremia, hypertriglyceridemia, hypercholesterolemia, hyperuricemia, and hypochloremic metabolic alkalosis. In case of overdose, seek immediate medical attention if severe hypotension or arrhythmias occur. Store this drug out of the reach of children, and keep it in a cool place away from moisture and direct sunlight.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with fever, blisters, skin peeling, pain in mouth/eyes mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, lightning-like headaches, seizures, confusion of consciousness, visual disturbances, paralysis, urination

Mild side effects

  • Peripheral edema
  • headache
  • dizziness
  • upper respiratory infection
  • nasopharyngitis
  • urinary tract infection
  • sialadenitis
  • leukopenia
  • thrombocytopenia
  • bone marrow suppression
Show 18 more
  • neutropenia
  • agranulocytosis
  • hemolytic anemia
  • aplastic anemia
  • drug hypersensitivity
  • hyperkalemia
  • hypokalemia
  • loss of appetite
  • diabetes
  • hypercalcemia
  • hyperglycemia
  • hypomagnesemia
  • hyponatremia
  • hypochloremia
  • hypertriglyceridemia
  • hypercholesterolemia
  • hyperuricemia
  • hypochloremic metabolic alkalosis

Not everyone experiences these, and they can vary from person to person.

Storage

This drug should be stored in a tightly closed container to prevent exposure to air or moisture. The recommended storage temperature is between 1°C and 30°C at room temperature.

Appearance and packaging

Appearance

Round film-coated tablet in reddish gray

Package unit

30 tablets/PPT [(10 tablets/Alu-Alu × 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.