Rimetpol Tablet 1/250mg

Adult dose

This medication is administered 1 to 2 times a day before or with meals. Dosage can be adjusted based on each patient's current treatment regimen, efficacy, and tolerability, and appropriate blood glucose monitoring should be conducted. Typically, treatment is initiated at a low dose, and dosage adjustments can be made considering the patient's current medications and blood glucose levels. In clinical trials, the initial daily dosage was glimepiride/metformin hydrochloride 2mg/500mg.

This medication can cause severe lactic acidosis or hypoglycemia, so caution is needed. In particular, if renal function declines rapidly, the drug may accumulate in the body, increasing the risk of lactic acidosis, so kidney function should be checked regularly. If there are signs of dehydration or severe diarrhea, vomiting, fever, etc., it is advisable to temporarily stop administration and consult a doctor. Moreover, when combined with other drugs that may affect kidney function, careful observation is required to prevent deterioration of kidney function. This medicine should not be administered to patients with insulin-dependent diabetes mellitus or acute metabolic acidosis, or severe liver or kidney functional impairment. It is also recommended that pregnant or breastfeeding women do not use this medicine. Patients with a high risk of hypoglycemia, particularly the elderly or those with irregular meals or poor nutritional status, require careful monitoring and dosage adjustment. Gastrointestinal symptoms (such as diarrhea, nausea, vomiting) can commonly occur during initial treatment but are usually temporary and may be alleviated by taking it with meals. If serious allergic reactions occur, inform medical personnel immediately, and hematological adverse reactions should also be monitored closely. This medicine may interact with other medications, so it is important to inform medical staff of all medications being taken and regular blood glucose and kidney function tests are necessary. Alcohol consumption may increase the risk of lactic acidosis, so it is advisable to avoid alcohol. This medicine has not been sufficiently verified for safety and efficacy in children, so caution should be exercised in its use. Elderly patients often have reduced kidney function, so it is recommended to adjust the dosage and conduct regular kidney function tests. In case of overdose, hypoglycemia or lactic acidosis may occur, so immediate medical attention is necessary. Additionally, caution is required when driving or operating machinery due to the risk of accidents from hypoglycemia or other side effects. Store this medicine out of the reach of children and do not transfer it to another container.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, hypotension, shock and other severe allergic reactions. Severe skin reactions: severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes. Respiratory issues: difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever. Liver abnormalities (jaundice): yellowing of skin or eyes, general lethargy. Serious neurological symptoms: sudden and severe headache, thunderclap headache.

Mild side effects

Gastrointestinal symptoms: diarrhea, nausea, vomiting, abdominal bloating, loss of appetite, indigestion, constipation, abdominal pain. Specific sensory abnormalities: discomfort, metallic taste, transient vision impairment. Skin reactions and hypersensitivity: erythema, itching, hives, rash. Hematological abnormalities: thrombocytopenia, leukopenia, hemolytic anemia, erythrocytopenia, agranulocytosis, pancytopenia. Vitamin B12 reduction. Liver abnormalities: increased intrahepatic enzymes, liver dysfunction.

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. Furthermore, it is important to store it at room temperature between 1°C and 30°C to maintain the drug's effectiveness.

Appearance

White rectangular film-coated tablet

Package unit

30 tablets/bottle - 30 tablets/bottle, 100 tablets/bottle - 100 tablets/bottle