Glitinaduo Tablet 2.5/1000 mg

Adult dose

This medication is administered twice daily with meals. 1. If currently not treated with metformin: Take this medication 2.5/500 mg twice daily, 1 tablet each time, and may increase up to 2.5/1000 mg, 1 tablet twice daily. 2. If sufficient blood sugar control cannot be achieved with metformin monotherapy: Administer linagliptin 2.5 mg twice daily and existing metformin dosage.

This medication may cause a rare but serious side effect known as lactic acidosis, so it should not be used by patients with impaired kidney function or liver dysfunction. It should not be administered to patients who are allergic to the active ingredients or have certain heart and kidney conditions such as type 1 diabetes, diabetic ketoacidosis, or acute myocardial infarction. Due to the risk of hypoglycemia, blood sugar levels should be closely monitored and dosages adjusted when used in conjunction with other hypoglycemic agents such as insulin or sulfonylureas. Elderly patients with decreased kidney function or those taking medications that affect kidney function should undergo regular kidney function tests, and this medication should be temporarily discontinued in situations where kidney function may rapidly decline. Skin conditions such as acute pancreatitis or bullous pemphigoid may occur, so if persistent, severe abdominal pain or skin rash develops during treatment, consult a physician immediately. It is advisable to avoid using this medication in pregnant women or nursing mothers, and if planning a pregnancy, alternative treatment options should be discussed with a physician. Safety and efficacy in children and adolescents have not been established, thus usage is not recommended for children under 10 years of age. Alcohol consumption should be avoided during treatment, as the risk of lactic acidosis may increase, especially in cases of acute alcohol intoxication. If administration of radiologic iodinated contrast agents is required, this medication should be discontinued for a certain period before and after the examination, and kidney function should be reassessed. In cases of overdose, the risk of lactic acidosis is increased, thus immediate hospital treatment is necessary, which may include blood dialysis. Store this medication in a place out of reach of children, avoid moisture, and do not transfer to another container.

Serious side effects

• Urticaria
• angioedema
• lactic acidosis
• pancreatitis
• bullous pemphigoid
• liver abnormalities (including jaundice)
• severe allergic reactions
• severe neurological symptoms
• severe edema
• acute myocardial infarction

Mild side effects

Nasopharyngitis, taste disturbance, cough, decreased appetite, diarrhea, constipation, nausea, vomiting, abdominal pain, pruritus, rash, decreased blood B12, mouth ulcer formation, abnormal liver function tests, hepatitis, erythema, joint pain without severe or disabling symptoms, increased lipase, increased amylase, increased triglycerides in the blood, dizziness, insomnia, depression, anxiety, itching, decreased hemoglobin, increased blood pressure, musculoskeletal pain, fatigue, runny nose

This medication is sensitive to air and moisture, thus it should be stored in a sealed container. It is important to maintain storage temperature between 1 degree and 30 degrees Celsius. This helps ensure the medication's effectiveness and maintain quality.

Appearance

Light pink, oblong, biconvex film-coated tablet

Package unit

PTP - 60 tablets/PTP [10 tablets/PTP X 6]