Medication info
Atovazin 20 mg (Atorvastatin Calcium Hydrate)

Atovazin 20 mg (Atorvastatin Calcium Hydrate)

Prescription medicationTablet
Ingredient · strength
Atorvastatin Calcium Hydrate›21.7mg / 1 tablet
Manufacturer / importer
영진약품(주)
Appearance
White, round film-coated tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201906438 · Approved 2019.09.11 · Insurance code 642405180

Summary

Main use
Reduction of the risk of myocardial infarction and stroke and improvement of hypercholesterolemia
Who uses it
Adults · Children
Adult dosage
For the treatment of hyperlipidemia, the recommended starting dose is 10 mg of atorvastatin once daily, but for patients requiring greater LDL cholesterol reduction, starting can be at 20 mg or 40 mg once daily. This medication is generally administered in dosage ranges of 10 to 80 mg once daily. Lipid levels should be analyzed and dosage adjusted within 2 to 4 weeks post initiation and dose adjustment. For patients with homozygous familial hypercholesterolemia, the usual dose is 10 to 80 mg once daily, either in combination with other lipid-lowering therapies (e.g., LDL apheresis) or when such treatments are not feasible.
Children's dosage
The recommended starting dose for pediatric patients with heterozygous familial hypercholesterolemia (10 to 17 years) is 10 mg once daily, and the recommended maximum dose is 20 mg once daily. The dosage should be adjusted at intervals of 4 weeks or more.

Ingredients

Manufacturer
영진약품(주)

Efficacy & effects

Reduction of the risk of myocardial infarction and stroke and improvement of hypercholesterolemia

  • Myocardial infarction
  • stroke
  • vascular interventions
  • chronic stable angina
  • retinopathy
  • albuminuria
  • congestive heart failure
  • angina
  • hypercholesterolemia
  • dyslipidemia
  • dysbetalipoproteinemia
  • elevated serum triglycerides
View approved original text

This medication helps reduce the risk of cardiovascular diseases and aids in the treatment of hyperlipidemia. Specifically, it decreases the risk of myocardial infarction and stroke in adults with risk factors for coronary heart disease and in patients with type 2 diabetes. It also contributes to protecting heart health by reducing the risk of non-fatal myocardial infarction, stroke, angina, and hospitalization for congestive heart failure in patients with clinical evidence. Regarding hyperlipidemia, it improves lipid levels in patients with primary and mixed dyslipidemia, dysbetalipoproteinemia, and hypertriglyceridemia, thereby reducing the burden of cardiovascular disease. Particularly, it is used as an adjunct to diet in children aged 10 to 17 years with heterozygous familial hypercholesterolemia. Overall, this medication is used to enhance health through the prevention of cardiovascular diseases and improvement of blood lipid levels.

Dosage and Administration

Adult dosage

For the treatment of hyperlipidemia, the recommended starting dose is 10 mg of atorvastatin once daily, but for patients requiring greater LDL cholesterol reduction, starting can be at 20 mg or 40 mg once daily. This medication is generally administered in dosage ranges of 10 to 80 mg once daily. Lipid levels should be analyzed and dosage adjusted within 2 to 4 weeks post initiation and dose adjustment. For patients with homozygous familial hypercholesterolemia, the usual dose is 10 to 80 mg once daily, either in combination with other lipid-lowering therapies (e.g., LDL apheresis) or when such treatments are not feasible.

Children's dosage

The recommended starting dose for pediatric patients with heterozygous familial hypercholesterolemia (10 to 17 years) is 10 mg once daily, and the recommended maximum dose is 20 mg once daily. The dosage should be adjusted at intervals of 4 weeks or more.

Precautions

This medication may cause unusual symptoms in the muscles, so if severe muscle pain or weakness occurs, or if creatine kinase levels significantly rise, discontinue use immediately and consult a doctor. This medication may affect liver function, so patients with active liver disease or abnormally high liver enzyme levels should not use it. Patients with a history of muscle disease or poor kidney function should use this medication with caution and may require regular testing. Women who are pregnant or may become pregnant, and breastfeeding women should not take this medication and should use appropriate contraceptive methods while on this medication. This medication should not be used by children, especially those under 10 years of age, and its long-term safety has not been established in children over 10. If taken with certain specific medications, drug concentrations may increase, raising the risk of side effects, so it is essential to inform your doctor or pharmacist of any other medications being taken. There is no specific antidote for overdose, and treatment should be based on symptoms, with monitoring of liver function and muscle enzyme levels. This medication should be stored out of reach of children and kept in its original container for safety. It is important to notify healthcare professionals immediately if symptoms such as muscle pain, weakness, or fever occur during this medication regimen and to seek testing. Regular liver function tests and monitoring of muscle condition are necessary with long-term use, and if any abnormal symptoms arise, the medication should be discontinued immediately.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

  • Weakness
  • lethargy
  • chest pain
  • peripheral edema
  • fatigue
  • fever
  • nasopharyngitis
  • hyperglycemia
  • hypoglycemia
  • weight gain
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  • loss of appetite
  • constipation
  • abdominal bloating
  • dyspepsia
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • belching
  • pancreatitis
  • oropharyngeal and laryngeal pain
  • nosebleed
  • insomnia
  • nightmares
  • headache
  • dizziness
  • paresthesia
  • sensory loss
  • taste disturbance
  • memory loss
  • peripheral neuropathy
  • myalgia
  • arthralgia
  • limb pain
  • musculoskeletal pain
  • muscle cramps
  • joint

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to protect it from air and moisture. It is best to maintain storage temperatures between 1 to 30 degrees Celsius at room temperature. Doing so will help retain the medication's efficacy and safety over time.

Appearance and packaging

Appearance

White, round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.