Esca Tablet 10/40 mg

Adult dose

The standard dose is 1 tablet once daily taken with water, regardless of meals. It is recommended to take at the same time each day (e.g., in the morning). The recommended dosages are as follows: - 5/20 mg: for patients whose blood pressure is not adequately controlled with amlodipine 5 mg or olmesartan medoxomil 20 mg monotherapy. - 10/20 mg: for patients whose blood pressure is not adequately controlled with olmesartan medoxomil 20 mg.

Child dose

Safety and efficacy in pediatric patients under 18 years have not been established.

This drug can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters; therefore, if pregnancy is confirmed, it should be stopped immediately. Patients with allergies to this medication, severe liver disease, severe aortic stenosis, biliary obstruction, those undergoing kidney dialysis, in a state of shock, certain diabetic patients, and those with severely impaired kidney function should not take this medication. Patients with low fluid volume or sodium may experience hypotension, so their status should be carefully monitored during use, and appropriate measures taken if blood pressure decreases. Due to the risk of rapid blood pressure drop from vasodilation, caution should be exercised in patients with aortic stenosis or severe obstructive coronary artery disease. Precaution is required for patients with heart failure, and regular tests are necessary as renal function changes may occur in patients with impaired kidney function. Patients with liver dysfunction should also be cautious when taking this medication. While taking this medication, side effects such as dizziness, headache, hypotension, edema, dyspepsia may occur; if these symptoms persist or worsen, consultation with a doctor is advised. Women who are pregnant or planning to become pregnant should choose other therapies with confirmed safety instead of this medication, and breastfeeding women should consider stopping breastfeeding or the medication as adverse reactions may occur in infants. This medication is not recommended for children under 18 years of age as safety and effectiveness have not been established. Elderly patients should start with a low dose, considering renal and liver function decline, and should be cautious about drug interactions. Overdose may present symptoms such as hypotension and increased heart rate; in such cases, immediate medical assistance is necessary. This drug should be stored in a tightly sealed container out of direct sunlight and moisture, and kept out of the reach of children.

Serious side effects

Urticaria, severe swelling (edema), difficulty breathing, chest tightness, dizziness, gallstones, worsening stroke, gum bleeding, vascular edema, rhabdomyolysis, acute renal failure, hair loss, liver dysfunction (jaundice), toxic epidermal necrolysis, severe neurological symptoms (dizziness, fainting, worsening stroke), hematuria, hyperkalemia, acute renal failure, severe edema or urination abnormalities associated with increased blood pressure, increased serum creatinine levels, increased uric acid levels.

Mild side effects

• Dizziness
• headache
• orthostatic hypotension
• drowsiness
• paresthesia
• sensory loss
• fainting
• vertigo
• palpitations
• rapid heartbeat

This medication must be stored in a tightly sealed container to avoid exposure to air or moisture. It is essential to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance

Brownish-red round film-coated tablets

Package unit

28 tablets/Alu-Alu[(14 tablets/Alu-Alu packaging x 2)]