Medication info

Ariranitidine Hydrochloride Tablet 150 mg

Prescription medicationTablet경구Expired
Ingredient · strength
Ranitidine Hydrochloride›168mg / 1 tablet
Manufacturer / importer
(주)아리제약
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Expired

MFDS item code 201906410 · Approved 2019.09.11

This product's status changed to Expired on 2024.09.11. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment for improvement of gastric and duodenal ulcers and gastric mucosal lesions (erosion, bleeding, etc.)
Who takes it
Adults · Children
Adult dose
As ranitidine, take 150 mg orally, twice daily in the morning and at bedtime. 1) For gastric and duodenal ulcers: Take 150 mg orally, twice daily, or 300 mg once daily at bedtime. Particularly, for patients with duodenal ulcers, taking 300 mg twice daily, in the morning and at bedtime, increases the treatment rate. The same applies to prevention in combination therapy due to NSAID administration.
Child dose
For children aged 8 to 18 years, the dosage may be 150 mg (2 mg per kg body weight) per dose, administered up to 2 times a day.

Ingredients

Manufacturer
(주)아리제약

Efficacy & effects

Treatment for improvement of gastric and duodenal ulcers and gastric mucosal lesions (erosion, bleeding, etc.)

  • Gastric and duodenal ulcers
  • Zollinger-Ellison syndrome
  • gastroesophageal reflux disease
  • Mendelson's syndrome
  • postoperative ulcers
  • gastric and duodenal ulcers due to NSAID administration
  • gastric mucosal erosion
  • gastric mucosal bleeding
  • gastric mucosal redness
  • gastric mucosal swelling
  • acute gastritis
  • exacerbation of chronic gastritis
View approved original text

This medication is effective for various gastrointestinal diseases, including gastric and duodenal ulcers, Zollinger-Ellison syndrome, and gastroesophageal reflux disease. It is particularly useful for the prevention and treatment of ulcers caused by surgical procedures or NSAID use. Additionally, it helps improve gastric mucosal lesions such as exacerbation of acute and chronic gastritis and upper gastrointestinal bleeding. This medication alleviates inflammation, bleeding, redness, and swelling in the gastric mucosa and is used to enhance gastrointestinal health.

How to take

Adult dose

As ranitidine, take 150 mg orally, twice daily in the morning and at bedtime. 1) For gastric and duodenal ulcers: Take 150 mg orally, twice daily, or 300 mg once daily at bedtime. Particularly, for patients with duodenal ulcers, taking 300 mg twice daily, in the morning and at bedtime, increases the treatment rate. The same applies to prevention in combination therapy due to NSAID administration.

Child dose

For children aged 8 to 18 years, the dosage may be 150 mg (2 mg per kg body weight) per dose, administered up to 2 times a day.

Precautions

This medication should not be used in patients with a known allergy to any of its components or with a history of acute porphyria. Additionally, patients with genetic issues such as lactose intolerance, lactase deficiency, or glucose-galactose malabsorption should not take this medication. Patients with poor kidney function may have delayed elimination of this medication, therefore the dosage should be reduced or the dosing interval increased, and cautious use is necessary for patients with impaired liver function. Patients with a history of drug allergy reactions, elderly patients, and those taking non-steroidal anti-inflammatory drugs (NSAIDs) should use this medication with caution. This medication may conceal symptoms of gastric cancer, so gastric ulcer patients or middle-aged patients with newly developed indigestion symptoms should verify whether it is cancer before use. Patients with gastric or duodenal ulcers infected with Helicobacter pylori should also receive eradication therapy. Rarely, this medication may cause severe allergic reactions or abnormalities in blood, liver dysfunction, heart issues, gastrointestinal symptoms, neurological symptoms, myalgia, or skin reactions; if any unusual symptoms occur, stop taking it immediately and consult healthcare professionals. Regular blood tests and liver and kidney function tests should be conducted during treatment to monitor the condition. Elderly patients, chronic lung disease patients, diabetics, and patients with weakened immunity may be at an increased risk of pneumonia when taking this medication, so caution is necessary. Avoid driving or operating dangerous machinery if dizziness or drowsiness occurs after taking this medication. This medication can affect the absorption or metabolism of other drugs, so inform healthcare professionals when taking other medications and monitor closely. Women who are pregnant or may become pregnant should carefully consider the benefits and risks of using this medication, and breastfeeding women should only take it when necessary. The safety for children has not been adequately established, so caution is needed in usage. No serious issues have been reported from overdose, but appropriate treatment such as vomiting or gastric lavage may be necessary. This medication should be kept out of reach of children, and transferring it to other containers should be avoided.

Side effects and when to seek care immediately

Serious side effects

  • Hives
  • angioedema
  • anaphylactic shock
  • bronchospasm
  • difficulty breathing
  • chest pain
  • severe allergic reactions
  • leukopenia
  • thrombocytopenia
  • bone marrow suppression
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  • aplastic anemia
  • agranulocytosis
  • pancytopenia
  • acquired immune hemolytic anemia
  • jaundice
  • hepatitis
  • severe skin reactions
  • bradycardia
  • heart block
  • vasculitis
  • acute pancreatitis
  • seizures
  • altered consciousness
  • myoclonus
  • severe neurological symptoms.

Mild side effects

Rash, fever, angioedema, low blood pressure, chest pain, granulocytopenia, increased serum creatinine, leukopenia, thrombocytopenia, bone marrow suppression, aplastic anemia, eosinophilia, transient and reversible liver dysfunction, bradycardia, heart block, tachycardia, vasculitis, constipation, nausea, vomiting, abdominal bloating, abdominal pain, loss of appetite, diarrhea, acute pancreatitis, dizziness, drowsiness, headache, heaviness in the head, insomnia, restlessness, anxiety.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a container that protects it from light. Also, it is important to maintain the medication's efficacy by storing it at room temperature between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.