PalmTalk Soft Capsule 30mg (Alitretinoin)

Adult dose

Take 10~30mg once daily with or immediately after a meal. It is preferable to take it at the same time each day. The initial dose is 30mg of alitretinoin, reduced to 10mg according to adverse reactions. Patients with diabetes, obesity, cardiovascular risk factors, or dyslipidemia: Administer an initial dose of 10mg; it may be increased to 30mg as needed according to tolerability and effect. Periodic monitoring of the blood lipid profile and blood glucose may be necessary during treatment with this medicine. Discontinue treatment as soon as the treatment goal of clear or almost clear hands is achieved. If hand eczema remains severe after the initial 12 weeks of treatment, discontinue treatment; also discontinue treatment if the treatment goal has not been achieved by Week 24.

This medication must not be taken by women who are pregnant or may become pregnant, as it poses a very high risk of causing serious birth defects. A pregnancy test must be conducted before taking this medication, and effective contraception must be used from before treatment initiation until one month after treatment cessation. If pregnancy is suspected or confirmed, discontinue use immediately and consult a physician. This medication may increase blood triglyceride and cholesterol levels, so lipid levels should be monitored regularly through blood tests. If triglyceride levels become excessively high, serious side effects such as acute pancreatitis may occur, and discontinuation may be necessary. As it can affect mental health, any signs of depression or mood changes must be reported to healthcare professionals immediately. Patients with a history of mental illness should be especially cautious. This medication is contraindicated or must be administered with caution in patients with poor liver or kidney function, thyroid disorders, or vitamin A excess. Sensitivity to ultraviolet light may increase during use, so it is advisable to avoid strong sunlight or light therapy and to use sunscreen. In case of overdose, symptoms may include headache, vomiting, diarrhea, facial flushing, and immediate medical attention should be sought. This medication should be taken with food, swallowed with water, and must not be chewed. When storing, keep out of reach of children, and store in a cool place (below 30 degrees Celsius) away from direct sunlight. Do not use expired medication. Finally, this medication should never be shared with others, and any leftover tablets after treatment should be returned to a pharmacist for safe disposal.

• Headache
• erythema
• flushing
• increased triglycerides
• increased cholesterol
• decreased thyroid-stimulating hormone
• decreased free T4
• anemia
• increased iron-binding capacity
• decreased monocytes

This medication may be sensitive to light, so it should be stored in a container that blocks light. Additionally, it is best to store the medication at room temperature, between 1 and 30 degrees Celsius, avoiding locations that are too hot or too cold, to maintain its effectiveness for a longer period.

Appearance

Brownish-red oval soft capsule containing a uniform yellow to yellow-green liquid.

Package unit

30 capsules/box [10 capsules/PTP x 3]