Birodi Tablets 5mg (Esamlodipine besilate hydrate)

Adult dose

As esamlodipine, the usual dose is 2.5 mg taken orally once daily, which may be increased up to a maximum of 5 mg per day depending on the patient's response. Take with sufficient amount of water.

This medication should not be used by certain patients. For example, those who have had allergic reactions to this drug, its components, or similar types of medications should avoid taking it. It is also safe to refrain from using this drug in women who are pregnant or may become pregnant, as well as those who are breastfeeding. Additionally, patients in cardiogenic shock, those with severe aortic stenosis, unstable angina, recent myocardial infarction, severe liver dysfunction, and those with severe hypotension should not take this medication. This medication contains lactose hydrate, so those with lactose intolerance or specific metabolic disorders should avoid using it. Patients with severe renal impairment, those undergoing dialysis, the elderly, patients with acute heart failure, hypertensive crisis, and those with mild to moderate liver dysfunction should use this medication cautiously. When taking this drug, symptoms such as warmth and facial flushing, fatigue or swelling, a sensation of rapid heart rate, dizziness, headache, nausea, drowsiness, and ankle swelling may occur. If such symptoms arise, it is advisable to consult a healthcare professional. Furthermore, this medication can interact with other drugs, so if you are taking any other medications, you must inform your healthcare provider. Caution is especially needed when taken with grapefruit juice, certain antibiotics, antihypertensives, and antidepressants. If you are pregnant or breastfeeding, it is best to avoid using this drug as its safety has not been established. If breastfeeding, you should discontinue breastfeeding while taking this medication. Use is recommended only for children over 6 years of age; the effects on children under 6 years are unknown. Elderly patients should start at a lower dose since the drug concentration in the body may increase and should be monitored closely. Discontinuing this medication suddenly can worsen symptoms; do not stop taking it without doctor’s advice. In case of overdose, severe hypotension, arrhythmias, shock, etc. may occur, requiring emergency treatment. This medication should be stored out of reach of children and should not be transferred to other containers.

Serious side effects

• Hives
• angioedema
• toxic epidermal necrolysis
• jaundice
• paralysis

Mild side effects

• Flushing with warmth
• fatigue
• swelling
• palpitations
• dizziness
• headache
• migraine
• weakness
• abdominal pain
• nausea

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is recommended to keep it at room temperature between 1 to 30 degrees Celsius. Avoid storing it in excessively hot or cold places.

Appearance

White octagonal tablets

Package unit

30 tablets/bottle, 300 tablets/bottle