Medication info
Barostat 40 mg Tablet (Atorvastatin Calcium Trihydrate)

Barostat 40 mg Tablet (Atorvastatin Calcium Trihydrate)

Prescription medicationTablet
Ingredient · strength
Atorvastatin Calcium Trihydrate›43.38mg / 1 tablet
Manufacturer / importer
삼익제약(주)
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201906327 · Approved 2019.09.05 · Insurance code 644004340

Summary

Main use
Reduction of the risk of myocardial infarction and stroke, and improvement of hyperlipidemia
Who uses it
Adults
Adult dosage
Atorvastatin is administered once daily at any time of day, regardless of meals. The recommended initial dose is 10 mg, and in cases where greater LDL cholesterol reduction is needed, it may start at 20 mg or 40 mg. The dosage range is from 10 to 80 mg. The initial and maintenance doses should be individualized based on the treatment goals and patient characteristics, and lipid levels should be re-evaluated within 2 to 4 weeks after initiation or dose adjustment.

Ingredients

Manufacturer
삼익제약(주)

Efficacy & effects

Reduction of the risk of myocardial infarction and stroke, and improvement of hyperlipidemia

  • Coronary heart disease
  • myocardial infarction
  • stroke
  • vascular invasive procedures
  • stable chronic angina
  • retinopathy
  • albuminuria
  • hypertension
  • type 2 diabetes
  • congestive heart failure
  • angina
  • hyperlipidemia
View approved original text

This medication helps reduce the risk of myocardial infarction, stroke, and vascular invasive procedures in adults with various risk factors for cardiovascular disease and in patients with diabetes. Additionally, it reduces the risk of hospitalization due to myocardial infarction, stroke, angina, and congestive heart failure in patients with heart disease. Furthermore, it is used to reduce total cholesterol, LDL cholesterol, Apo-B protein, and triglyceride levels while increasing HDL cholesterol in patients with hyperlipidemia, thereby improving blood lipid levels. This drug is also effectively used as an adjunct in various types of dyslipidemia that do not respond well to dietary changes. Thus, this medication is used beneficially to maintain cardiovascular health and manage hyperlipidemia.

Dosage and Administration

Adult dosage

Atorvastatin is administered once daily at any time of day, regardless of meals. The recommended initial dose is 10 mg, and in cases where greater LDL cholesterol reduction is needed, it may start at 20 mg or 40 mg. The dosage range is from 10 to 80 mg. The initial and maintenance doses should be individualized based on the treatment goals and patient characteristics, and lipid levels should be re-evaluated within 2 to 4 weeks after initiation or dose adjustment.

Precautions

This medication can affect the muscles; therefore, if there are severe muscle pain or weakness, or if muscle enzyme levels significantly increase, discontinue use immediately and consult a doctor. This drug should not be used in individuals with certain liver diseases or those with significantly elevated liver enzyme levels, or in those with muscle disorders. This medication is not given to pregnant women, those who may become pregnant, nursing mothers, or children under 10 years of age. Since this medication can affect liver function, regular liver function tests should be performed before and during treatment, and if symptoms of hepatitis or jaundice occur, the doctor should be notified immediately. Patients who consume a lot of alcohol or have a history of liver disease should use this medication cautiously. Increased plasma concentrations of this drug can heighten the risk of muscle damage; therefore, careful consideration is needed when taken with certain antibiotics, antifungals, or antivirals. It is advisable to avoid grapefruit juice during treatment, and to consult a doctor or pharmacist when taking this drug along with other medications. If symptoms such as muscle pain, weakness, or fever occur during treatment, notify a doctor immediately for evaluation. Elderly patients or those with reduced kidney function are at a higher risk of muscle damage, so careful observation is required during use. Women of childbearing age should use appropriate contraceptive methods while taking this drug, and if pregnancy is confirmed, the medication should be discontinued immediately. This medication is not recommended for nursing women, and breastfeeding should be discontinued during treatment. There is no specific antidote for overdose; therefore, treatment is symptomatic, and liver function and muscle enzyme tests should be conducted. This medication should be kept out of reach of children and stored in its original container to prevent deterioration.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reaction, high fever with severe rash, blisters, skin peeling, oral/ocular mucosal pain, severe skin adverse reactions, difficulty breathing or shortness of breath, asthma attack, abnormal breathing with cough and fever, respiratory problems, yellowing of the skin or eyes (jaundice), extreme tiredness, liver dysfunction (jaundice), sudden and

Mild side effects

  • Weakness
  • fatigue
  • chest pain
  • peripheral edema
  • tiredness
  • fever
  • nasopharyngitis
  • hyperglycemia
  • hypoglycemia
  • weight gain
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  • loss of appetite
  • constipation
  • abdominal distension
  • dyspepsia
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • belching
  • pancreatitis
  • pharyngeal and laryngeal pain
  • nosebleed
  • insomnia
  • nightmares
  • headache
  • dizziness
  • paresthesia
  • sensory loss
  • taste disturbance
  • memory loss
  • peripheral neuropathy
  • myalgia
  • arthralgia
  • limb pain
  • musculoskeletal pain
  • muscle cramps
  • joint pain

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a tightly closed container to prevent air or moisture from entering. It is also important to keep it at room temperature, between 1 to 30 degrees Celsius, avoiding extremely hot or cold places.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.