Medication info
Losarplus F Tablet

Losarplus F Tablet

Prescription medicationTablet
Ingredient · strength
Losartan Potassium›100mg / 1 tabletHydrochlorothiazide›25mg / 1 tablet
Manufacturer / importer
한국휴텍스제약(주)
Appearance
Pale yellow oval film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201906270 · Approved 2019.09.03 · Insurance code 649104570

Summary

Main use
Improvement of blood pressure control in hypertension unresponsive to monotherapy
Who uses it
Adults · Children
Adult dosage
The usual dose of this medication is 50 mg of losartan potassium and 12.5 mg of hydrochlorothiazide administered once daily. Doses exceeding 100 mg of losartan potassium and 25 mg of hydrochlorothiazide per day are not advisable. Patients whose blood pressure is not controlled by monotherapy with losartan or hydrochlorothiazide will begin treatment with 50 mg of losartan potassium and 12.5 mg of hydrochlorothiazide administered once daily.
Children's dosage
There is no experience in using this drug in children and adolescents (under 18 years old), therefore combination therapy with losartan and hydrochlorothiazide should not be administered.

Ingredients

Manufacturer
한국휴텍스제약(주)

Efficacy & effects

Improvement of blood pressure control in hypertension unresponsive to monotherapy

  • Hypertension
View approved original text

This medication is used additionally for patients with hypertension that is not adequately controlled with monotherapy, helping to effectively lower blood pressure. In other words, it plays an adjunctive role in the treatment of hypertension that is difficult to control with monotherapy, thereby improving blood pressure control.

Dosage and Administration

Adult dosage

The usual dose of this medication is 50 mg of losartan potassium and 12.5 mg of hydrochlorothiazide administered once daily. Doses exceeding 100 mg of losartan potassium and 25 mg of hydrochlorothiazide per day are not advisable. Patients whose blood pressure is not controlled by monotherapy with losartan or hydrochlorothiazide will begin treatment with 50 mg of losartan potassium and 12.5 mg of hydrochlorothiazide administered once daily.

Children's dosage

There is no experience in using this drug in children and adolescents (under 18 years old), therefore combination therapy with losartan and hydrochlorothiazide should not be administered.

Precautions

This medication can severely harm the fetus when taken during pregnancy, especially in the second and third trimesters, so it must be discontinued immediately upon confirmation of pregnancy. It should not be administered to patients with hypersensitivity to this drug, certain renal and liver diseases, or lactose intolerance. Patients with hypotension, reduced kidney function, liver disease, or electrolyte imbalance should use this medication carefully, with particular caution for the elderly or patients with diabetes or gout. During treatment, blood pressure may drop too low, so if symptoms such as dizziness or fainting occur, medical consultation should be sought immediately. This medication can affect potassium levels in the blood, so it should be taken with caution not to combine it with potassium supplements or potassium-containing salt substitutes. Furthermore, this medication may increase the risk of skin cancer, so it is advisable to avoid sun exposure and regularly check skin conditions. Regular blood tests should be performed to monitor kidney function and electrolyte status during treatment, and any abnormal symptoms should be reported to medical personnel immediately. Caution is needed while driving or operating machinery, as dizziness or drowsiness may occur.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/eye mucous membranes, shortness of breath or difficulty breathing, asthma attack, breathing abnormalities accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, urination

Mild side effects

  • Abdominal pain
  • swelling
  • palpitations
  • back pain
  • dizziness
  • cough
  • sinusitis
  • upper respiratory infection
  • weakness/fatigue
  • diarrhea
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  • nausea
  • headache
  • bronchitis
  • pharyngitis
  • chest pain
  • facial swelling
  • fever
  • orthostatic hypotension
  • fainting
  • angina
  • arrhythmia
  • hypotension
  • myocardial infarction
  • secondary atrioventricular block
  • loss of appetite
  • constipation
  • toothache
  • dry mouth
  • dyspepsia
  • flatulence
  • gastritis
  • vomiting
  • lethargy
  • anemia
  • gout
  • arm pain
  • joint pain
  • arthritis
  • fibromyalgia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a special container to protect it from light and air, preferably at room temperature between 1°C and 30°C. Proper storage will help maintain the efficacy and safety of the medication.

Appearance and packaging

Appearance

Pale yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.