Novas Tablets (Amlodipine Besylate)

Adult dose

Adults: 5 mg of amlodipine is administered once daily orally, and can be increased to a maximum of 10 mg per day based on the patient's response. Adjustments should be made according to age and symptoms.

This medication should not be administered to certain patients. For instance, it should not be used in patients with allergies to this medication or similar drugs, nursing mothers, patients with severe liver dysfunction, patients with severe aortic stenosis, and patients in shock. Additionally, it should be used with caution in patients with severe hypotension, those requiring dialysis for renal failure, the elderly, pregnant women, or women who may become pregnant. Especially in case of pregnancy, careful consideration is necessary, with use recommended only when no safe alternative medication is available. Various side effects can occur while taking this medication. The most common side effects include facial flushing, fatigue, swelling, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea. Rarely, symptoms such as decreased blood pressure, neurological problems, gastrointestinal issues, skin rashes, and liver dysfunction have been reported, so immediate consultation with a physician is required if any abnormal symptoms appear. Patients with heart failure should exercise caution as this drug may cause pulmonary edema, and patients with impaired liver function may require dose adjustments as its effects may last longer. This drug has a slow onset of action, hence it is not suitable for the treatment of acute angina. It is known to have little effect on driving or machine operation abilities, but individual responses may vary, thus caution should be exercised. This drug can interact with several other medications, so if any other drugs are being taken, the healthcare provider must be informed. Particular caution is required when used in conjunction with certain antibiotics, antihypertensives, statins, and immunosuppressants. Safety during pregnancy or lactation has not been established, so its use should be avoided whenever possible or discussed with a healthcare provider beforehand. It is recommended to discontinue breastfeeding while taking this medication. Use in children is recommended only for those aged 6 years or older, as safety and efficacy have not been established below this age. Older adults can be given the standard dosage, but caution should be taken according to their physical condition. In case of overdose, severe hypotension and cardiac problems may occur, necessitating immediate emergency treatment. This medication is not removed by hemodialysis, so professional treatment is essential.

Serious side effects

Urticaria, angioedema, polymorphic erythema → severe allergic reactions; hepatitis, jaundice → liver dysfunction (jaundice); dyspnea → respiratory issues; toxic epidermal necrolysis → severe skin reactions.

Mild side effects

• Facial flushing
• fatigue
• swelling
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication can be sensitive to air or moisture, thus it should be stored in a tightly closed container. It is important to maintain a storage temperature of 1 to 30 degrees Celsius to preserve its effectiveness and prevent deterioration.

Appearance

White octagonal tablet

Package unit

Domestic use - 30 tablets/bottle, Domestic use - 300 tablets/bottle