Roxonarin Tablets (Roxoprofen Sodium)

Adult dose

1. For indications 1, 2: The adult dosage of roxoprofen sodium (anhydrous) is 60 mg orally three times a day. For single doses, administer 60-120 mg orally. 2. For indication 3: The adult dosage of roxoprofen sodium (anhydrous) is 60 mg orally. Typically, it can be administered twice a day, with a maximum daily dosage of 180 mg. It is advisable to avoid administration on an empty stomach.

This medication may cause gastrointestinal bleeding in individuals who regularly consume more than three alcoholic drinks each day; therefore, consultation with a doctor or pharmacist is necessary. Individuals with cardiovascular diseases or risk factors should exercise caution as serious cardiovascular issues such as myocardial infarction or stroke may occur when taking this medication. This medication poses a risk of severe gastrointestinal problems such as bleeding, ulcers, and perforation, so especially elderly patients or individuals with a history of gastrointestinal diseases should be more careful. Patients with a history of peptic ulcer, severe blood abnormalities, or significantly reduced liver or kidney function should not take this medication, and those allergic to aspirin or other non-steroidal anti-inflammatory drugs should avoid it as well. Patients with a history of peptic ulcer or issues regarding kidney, liver, or blood should be closely monitored by a physician when using this medication. If any allergic reactions occur during usage, such as skin rash, itching, hives, difficulty breathing, or low blood pressure, discontinue use immediately and consult healthcare personnel. If gastrointestinal symptoms such as abdominal pain, nausea, vomiting, or bloody stools arise, discontinue medication immediately and seek treatment. This medication may cause neurological side effects such as drowsiness, dizziness, or headache; caution is advised when driving or operating machinery. Regular monitoring and observation are necessary due to the risk of worsening liver or kidney function, and if any abnormal symptoms occur, the medication should be stopped. The risk of side effects increases when this medication is taken with other non-steroidal anti-inflammatory drugs, so it is better to avoid this combination. Additionally, interactions may occur with blood pressure medications, diuretics, anticoagulants, lithium, methotrexate, etc., so inform the doctor of any current medications being taken. This medication should not be used in late pregnancy as it may pose risks to the fetus, and it should be used cautiously in early or mid-pregnancy. It is advised not to take this medication while breastfeeding. Safety for pediatric use has not been established, so it is not recommended for children. Elderly patients should take this medication with extra caution due to a higher risk of side effects. This medication should be used at the lowest effective dose for the shortest duration, and if any adverse reactions occur during use, consult healthcare personnel immediately. Keep out of reach of children and do not transfer to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, peptic ulcer, perforation, hematemesis, melena, bloody stool, shock, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), erythema multiforme, acute generalized exanthematous pustulosis, aseptic meningitis (fever, headache, nausea, vomiting, neck stiffness, altered consciousness), angioedema, facial swelling (periorbital edema, oral edema), obstruction and pulmonary issues.

Mild side effects

• Rash
• itching
• fever
• abdominal pain
• discomfort in the upper abdomen
• decreased appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication may be sensitive to air and moisture; thus, it should be stored in a tightly sealed container. It is best to maintain storage temperatures between 1 to 30 degrees Celsius room temperature. This will help preserve the medication's efficacy and ensure safe use.

Appearance

White circular tablet

Package unit

For internal use - 30 tablets/bottle, For internal use - 600 tablets/bottle