Medication info
Nexium 20mg (Esomeprazole Magnesium Trihydrate)

Nexium 20mg (Esomeprazole Magnesium Trihydrate)

Prescription medicationTablet경구 · 정맥
Ingredient · strength
Esomeprazole Magnesium Trihydrate›22.25mg / 1 tablet
Manufacturer / importer
대웅바이오(주)
Appearance
Pink round film-coated tablet
Packaging
28 tablets/box [(14 tablets/PTP x 2)]
Approval status
Active

MFDS item code 201906199 · Approved 2019.08.30 · Insurance code 694002600

Summary

Main use
Treatment of gastroesophageal reflux disease (erosive reflux esophagitis, etc.), eradication of Helicobacter pylori, prevention of recurrence of peptic ulcer, and relief of gastrointestinal symptoms related to NSAIDs.
Who uses it
Adults · Children
Adult dosage
This medication should be swallowed with liquid such as water, and should not be chewed or crushed. Take once daily, either 20 mg or 40 mg. - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. Extend for an additional 4 weeks if not resolved. - Maintenance therapy for prevention of esophagitis recurrence: once daily, 20 mg. - Symptom treatment for gastroesophageal reflux disease without esophagitis: once daily,
Children's dosage
Adolescents aged 12 and older: - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. Extend for an additional 4 weeks if not resolved. - Symptom treatment for gastroesophageal reflux disease without esophagitis: once daily for 1

Ingredients

Manufacturer
대웅바이오(주)

Efficacy & effects

Treatment of gastroesophageal reflux disease (erosive reflux esophagitis, etc.), eradication of Helicobacter pylori, prevention of recurrence of peptic ulcer, and relief of gastrointestinal symptoms related to NSAIDs.

  • Gastroesophageal reflux disease
  • erosive reflux esophagitis
  • esophagitis
  • duodenal ulcer
  • peptic ulcer
  • upper gastrointestinal pain
  • upper gastrointestinal discomfort
  • upper gastrointestinal burning sensation
  • gastric ulcer
  • duodenal ulcer
  • Zollinger-Ellison syndrome
  • rebleeding of gastric ulcer
View approved original text

This medication is used for the treatment of gastroesophageal reflux disease and erosive reflux esophagitis, and is effective for long-term maintenance therapy to prevent recurrence of esophagitis. Additionally, it is utilized in combination antibiotic therapy for the treatment of duodenal ulcers and peptic ulcers positive for Helicobacter pylori. It also aids in relieving gastrointestinal symptoms associated with NSAIDs, treating gastric ulcers, and preventing related ulcers. It is also used in the treatment of Zollinger-Ellison syndrome and as maintenance therapy to prevent rebleeding of gastric ulcers and duodenal ulcers. Thus, it is effective for the treatment and prevention of recurrence of various gastrointestinal diseases.

Dosage and Administration

Adult dosage

This medication should be swallowed with liquid such as water, and should not be chewed or crushed. Take once daily, either 20 mg or 40 mg. - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. Extend for an additional 4 weeks if not resolved. - Maintenance therapy for prevention of esophagitis recurrence: once daily, 20 mg. - Symptom treatment for gastroesophageal reflux disease without esophagitis: once daily,

Children's dosage

Adolescents aged 12 and older: - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. Extend for an additional 4 weeks if not resolved. - Symptom treatment for gastroesophageal reflux disease without esophagitis: once daily for 1

Precautions

This medication should not be used in patients with specific allergies or hypersensitivity. Especially, those allergic to this medication, its components, and specific antibiotics or other drugs should avoid taking it. It is advisable for pregnant or breastfeeding women to avoid this medication, and patients with heart disease or those who have previously experienced myocardial infarction should exercise caution. Various side effects may appear during the use of this medication, including headaches, abdominal pain, diarrhea, nausea, skin rashes, and myalgia, so if any abnormal symptoms occur, consult healthcare professionals immediately. When taking this medication for a long time, regular check-ups are important to monitor bodily conditions, particularly since magnesium levels may decrease. This medication may interact with other drugs, so if you are currently taking other medications, you must inform your doctor or pharmacist, particularly regarding antiviral agents, antibiotics, anticoagulants, etc. Long-term or high-dose use of this medication may increase the risk of fractures, so individuals at risk for osteoporosis should consult their doctor for appropriate monitoring. During the use of this medication, there may be a slight increase in the risk of gastrointestinal infections, so if symptoms of diarrhea persist or worsen, inform healthcare providers immediately. In case of overdose, there is no specific antidote, so it is important to receive appropriate treatment based on symptoms, and keep it in a safe place out of the reach of children.

Side effects and when to seek care immediately

Serious side effects

  • Urticaria
  • severe swelling (angioedema)
  • anaphylaxis reaction/shock
  • severe allergic reaction
  • severe rash with fever
  • blisters
  • skin peeling
  • pain in oral/ocular mucosa
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
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  • mucocutaneous syndrome
  • liver abnormalities (jaundice)
  • hepatitis
  • liver failure
  • encephalopathy
  • obstructive jaundice
  • sudden and severe headache
  • paralysis
  • seizures
  • consciousness disturbances
  • visual disturbances
  • severe headache
  • rhabdomyolysis

Mild side effects

Headache, dizziness, insomnia, anxiety, mental confusion, depression, aggression, hallucinations, taste disturbances, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, dermatitis, itching, rash, alopecia, photosensitivity, arthralgia, myalgia, weakness, increased sweating, Clostridium difficile-associated diarrhea, allergic reactions, chest pain, facial swelling, facial flushing, fatigue, fever,

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. It is advisable to maintain the storage temperature between 1 degree and 30 degrees Celsius.

Appearance and packaging

Appearance

Pink round film-coated tablet

Package unit

28 tablets/box [(14 tablets/PTP x 2)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.