Dihacen Capsule (Dihydroquercetin)

Adult dose

Adults: Administer diacerein 50∼100mg per day orally in 1∼2 divided doses after meals. Adjust the dose as appropriate according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily is recommended for the first 2-4 weeks, followed by 50mg twice daily.

This medication should not be used in patients with specific diseases. Do not administer to patients with inflammatory bowel disease such as ulcerative colitis or Crohn's disease, those with intestinal obstruction syndrome, or patients with unexplained abdominal pain. Additionally, patients with allergies to this drug, its ingredients, or Rhein-type drugs should not use it. Patients with liver disease or a history of liver disease, as well as children under 15 years of age, should also avoid this medication. This product contains lactose and should not be administered to patients with genetic issues like galactose intolerance, lactase deficiency, or glucose-galactose malabsorption. This medication should be used cautiously in patients with a history of small intestine or colon disease. Pregnant or nursing women and elderly individuals over 65 should take a reduced dose or use it carefully. This medication may cause diarrhea, loose stools, and abdominal pain in the digestive system. Prolonged use may result in serious gastrointestinal complications such as gastrointestinal bleeding, ulcers, or perforations, and rare instances of pigmentation in the rectal mucosa may occur. Severe diarrhea may lead to dehydration and electrolyte imbalance, so caution is needed. Skin reactions like itching, rash, and eczema are common. It may affect liver function, leading to elevated liver enzyme levels, so hepatic health should be monitored periodically. When using this medication long-term, it is essential to follow the physician's instructions. If diarrhea occurs, discontinue use immediately and consult a physician; avoid taking it along with laxatives. Due to the risk of liver damage, if symptoms of liver injury appear, discontinue use and consult a physician. Additionally, it is advisable to limit alcohol intake while on this medication. This medication may interfere with the absorption of antacids containing calcium, magnesium, or aluminum, or salt, so maintain a gap of at least 2 hours before taking them together. Caution is required when used with diuretics as it may enhance the diuretic effect, leading to dehydration or hypokalemia. Care should also be taken when used concurrently with cardiotonic drugs as it may increase the risk of arrhythmias. Pregnant or nursing women are advised to avoid this medication. Animal studies have reported delayed bone formation in fetuses, and the effects on humans are not clearly understood as some components may transfer through breast milk. In case of overdose, severe diarrhea may occur, and necessary treatments, including electrolyte replenishment, should be provided.

Diarrhea, loose stools, abdominal pain, gastrointestinal disturbances (bleeding, ulcers, and perforation), pigmentation of the rectal mucosa, itching, rash, eczema, elevation of serum liver enzymes

This medication should be stored in a tightly closed container to prevent air or moisture ingress. It is advisable to maintain storage temperatures between 1 to 30 degrees Celsius.

Appearance

A hard capsule with a yellow upper half and a white lower half filled with yellow crystalline powder.

Package unit

30 capsules/bottle, 100 capsules/bottle, 500 capsules/bottle, 1000 capsules/bottle