Nebivolol and Rosuvastatin Tablets 2.5/10mg (Nebivolol, Rosuvastatin)

Adult dose

This medication is prescribed for patients taking nebivolol and rosuvastatin simultaneously for convenience. The patient will switch to this combination medication (containing the same dosages of nebivolol and rosuvastatin as individual medications) and take one tablet once daily.

This medication should not be administered to certain patients, such as those with allergies to its components, those with severely impaired liver function, patients with bradycardia, severe heart failure, hypotension, or those with cardiac conduction disorders, as it may pose risks. Additionally, it should not be administered or used with extreme caution in pregnant or nursing women, or in women of childbearing potential who are not using appropriate contraceptive measures. High-dose administration is contraindicated for patients with a history of muscle diseases or a high risk of muscle damage. This medication contains lactose, so patients with lactose intolerance should not take it. There are also patients who require careful administration, such as those with chronic lung disease, heart failure, peripheral vascular disease, thyroid abnormalities, and diabetes mellitus; these patients should be closely monitored while taking this medication. If symptoms such as muscle pain or muscle weakness occur, medical personnel should be notified immediately, and blood tests should be performed to check for muscle damage if necessary. This medication can affect the liver and muscles; therefore, regular liver function tests and muscle-related tests should be conducted before and during administration. This medication can interact with multiple drugs, so if other medications are being taken, it is crucial to inform healthcare professionals. Particular caution is needed when used concomitantly with certain antiarrhythmics, calcium channel blockers, antidepressants, and anticonvulsants. During pregnancy or lactation, this medication should be avoided as it may be harmful to the fetus or newborn. Women of childbearing potential should use appropriate contraceptive methods. It is not recommended for children and adolescents under 18 years old, as safety and efficacy have not been established. For elderly patients, it should be started at a low dose and administered while closely monitoring their condition to avoid excessive blood pressure reduction. In case of overdose, symptoms such as reduced heart rate, hypotension, and respiratory distress may occur, requiring immediate medical treatment. This medication may cause dizziness during driving or operating machinery, so caution is advised. Finally, this medication should be kept out of the reach of children and stored in its original container to prevent misuse or quality deterioration.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with fever, blisters, skin peeling, pain in the oral/eye mucosa, difficulty or trouble breathing, asthma attack, cough with fever accompanied by respiratory difficulties, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

• Eye discharge
• discomfort in the upper abdomen
• gastritis
• gastroesophageal reflux disease
• chest pain
• nasopharyngitis
• flu
• increased CK
• increased ALT
• increased AST

This medication may be sensitive to air or moisture; therefore, it should be stored in a tightly sealed container. The medication should be kept away from extremes of temperature and stored at room temperature between 1°C and 30°C.

Appearance

White to almost white round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle, 30 tablets/box [10 tablets/PTP*3]