Losacal Plus Tablet

Adult dose

Start with 1 tablet of Losartan Potassium 50 mg / Hydrochlorothiazide 12.5 mg once daily. If blood pressure is not controlled after 3 weeks, the dosage may be increased to a maximum of Losartan Potassium 100 mg / Hydrochlorothiazide 25 mg once daily. Patients with renal impairment should use the standard dosage if creatinine clearance is 30 mL/min or more; administration is not recommended for patients with severe renal impairment.

Child dose

There is no experience using this medication in children and adolescents (under 18 years old), so it should not be administered.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. Women of childbearing age should avoid taking this medication. People who are allergic to this drug or any of its components should not take it. Patients with severely impaired kidney function or those undergoing dialysis should not take this medication. Patients with hypotension, kidney problems, liver disease, hyperuricemia, gout, electrolyte imbalance, etc., should use this medication cautiously and follow their doctor's instructions. As this drug lowers blood pressure, dizziness or drowsiness may occur during use, so caution is required when driving or operating machinery. During treatment, potassium supplements or potassium-containing salt substitutes should not be taken without consulting a doctor. Due to the presence of hydrochlorothiazide, electrolyte status must be monitored regularly, and if symptoms of dehydration or electrolyte imbalance occur, immediate consultation with healthcare professionals is necessary. This medication may increase the risk of skin cancer when exposed to sunlight, so UV protection and monitoring of skin condition are required during treatment. Elderly patients may experience adverse reactions more frequently when taking this medication, so caution is necessary. This drug may interact with other antihypertensive medications or drugs, so if you are taking other medications, be sure to inform your doctor or pharmacist. Pregnant or nursing women should consult with their doctor before taking this medication and should carefully consider whether to continue breastfeeding while on it.

Serious side effects

Urticaria, angioedema (swelling of the lips and eyelids and facial rash), skin peeling phenomenon, hemolysis, severe allergic reactions (including urticaria and angioedema), intrahepatic cholestatic jaundice, acute respiratory distress syndrome (ARDS), pneumonia and pulmonary edema, acute renal failure, renal failure, hepatitis, thrombocytopenia, vasculitis, anaphylaxis, jaundice, sudden and very severe headache, seizures, confusion, visual disturbances, paralysis,

Mild side effects

• Abdominal pain
• swelling/tumefaction
• palpitations
• low back pain
• dizziness
• cough
• sinusitis
• upper respiratory infection
• weakness/fatigue
• diarrhea

This medication is sensitive to light and should be stored in a container that blocks light. It is also recommended to store it at room temperature between 1 degree and 30 degrees Celsius.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle