Pampein Pro Soft Capsule (Dexibuprofen)

Adult dose

As dexibuprofen, take 300 mg orally 2 to 4 times a day. However, do not exceed a total of 1,200 mg of dexibuprofen in one day.

This medication may cause gastrointestinal bleeding if taken regularly by individuals who consume more than three alcoholic drinks per day; therefore, consultation with a physician or pharmacist is essential. This medication can increase the risk to the cardiovascular system, and patients with cardiovascular diseases or risk factors should be particularly vigilant and closely monitor for cardiovascular symptoms with their doctor. Severe adverse reactions such as gastrointestinal bleeding, ulcers, or perforation may occur; hence, elderly patients or those with a history of gastrointestinal diseases should be especially careful. Patients with gastrointestinal ulcers or bleeding, severe hematological abnormalities, liver dysfunction, kidney dysfunction, heart failure, or severe hypertension should not take this medication. Taking this medication in conjunction with aspirin or other non-steroidal anti-inflammatory drugs may increase the risk of gastrointestinal adverse reactions, so it is advisable not to combine them. While taking this medication, caution is advised while driving or operating machinery due to the risk of accidents from dizziness or fatigue. Pregnant women, especially after the sixth month of pregnancy, should avoid taking this medication as it may affect the fetus. This medication is also passed into breast milk and can cause adverse reactions in infants, so breastfeeding should be avoided or stopped if taking this medication. Regular blood tests, liver function tests, and kidney function tests should be conducted to check for abnormalities during prolonged or high-dose administration. This medication may cause skin rashes, anaphylaxis, or severe allergic reactions in some patients; if symptoms occur, cease taking the medication immediately and consult a doctor. Patients with hypertension or heart failure should closely monitor for changes in blood pressure and fluid retention when taking this medication. This medication interacts with many other drugs, so it is crucial to consult healthcare providers if taking concomitant medications. In case of overdose, immediate medical intervention is required, and rapid measures such as gastric lavage or induced vomiting may be necessary. This medication should be stored away from children and kept in a tightly sealed container, avoiding direct sunlight and maintaining a cool, dry place.

Serious side effects

• Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, rarely occurring shock, severe allergic reactions
• Severe rash accompanied by high fever, blisters, peeling skin, pain in oral/ocular mucosa, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell’s syndrome), DRESS syndrome, AGEP
• Breathlessness or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever
• Skin or eye jaundice

Mild side effects

• Dyspepsia
• abdominal bloating
• heartburn
• pain in the upper abdomen
• diarrhea
• constipation
• loss of appetite
• nausea
• vomiting
• abdominal pain

Drug interactions

This medication should not be used with other non-steroidal anti-inflammatory drugs, aspirin, or high doses of methotrexate. Corticosteroids, alcohol, digoxin, phenytoin, probenecid, sulfinpyrazone, sulfonylureas, ACE inhibitors or angiotensin II receptor antagonists, diuretics, lithium, coumarin anticoagulants, baclofen, immunosuppressants, thrombolytics, ticlopidine, anticoagulants, and potassium concentrations in the blood are also included.

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture. It is also essential to keep it at temperatures between 1°C and 30°C to maintain its effectiveness.

Appearance

Transparent orange oval soft capsules filled with a colorless transparent liquid

Package unit

PTP - 12 capsules/PTP