Celeres Capsule 200 mg (Celecoxib)

Adult dose

The minimum recommended dose of this drug should be adjusted according to the patient, and it may be administered regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take celecoxib 200 mg once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS): Administer celecoxib 200 mg once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks at 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea: The initially recommended dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day onward, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

It is essential for individuals who drink heavily on a daily basis to consult a doctor or pharmacist before taking this medication, as it may cause gastric bleeding otherwise. Additionally, this medication may increase the risk of cardiovascular issues such as heart attack or stroke, thus it should only be used at the minimum effective dosage and for the shortest duration necessary. It may pose a risk of gastric ulcers or bleeding, so if any gastric-related symptoms occur, immediate medical consultation is required. This medication is not indicated for patients with specific allergies or liver and kidney diseases, as well as in pregnant or breastfeeding women, and those with cardiovascular diseases. Patients with compromised liver or kidney function, asthma, hypertension, or heart failure should use caution when taking this medication, as regular check-ups and monitoring are required. During treatment, one may experience dizziness or drowsiness, so it is advisable to avoid driving or operating machinery. This medication may interact with other drugs, so it is critical to inform healthcare professionals about any other medications being taken. Women contemplating pregnancy should consult a doctor prior to taking this medication, as it may affect reproductive capability. Elderly individuals may have decreased kidney, liver, or heart function and therefore require more careful observation during treatment. Those taking this medication long-term should undergo regular blood tests and liver-kidney function assessments, and should contact medical personnel immediately if any abnormal symptoms arise. If significant allergic reactions such as skin rash, itching, fever, or mucosal lesions occur, drug intake must be stopped immediately, and the hospital should be visited. In the case of overdose, symptoms such as nausea, vomiting, drowsiness, and gastric bleeding may appear, necessitating immediate emergency treatment. Safety and efficacy for children and adolescents have not been established, and use is not recommended.

Gastrointestinal bleeding, cardiovascular thrombotic reactions, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonia, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, flatulence, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, increased liver enzymes, itching, rash, hives, purpura, angioedema, alopecia, bullous dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disorders, albuminuria, cystitis, hematuria, dysuria, increased urinary frequency, nephrolithiasis, urinary incontinence, urinary tract infection, visual disturbances, cataract, conjunctivitis, eye pain, glaucoma, ocular bleeding, retinal artery or vein occlusion, increased blood creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, increased blood sodium, increased blood potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, synovial bursitis, arthralgia, arthrosis, skeletal deformities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, leg cramps, fractures, tendon ruptures, pain in various areas, muscle rigidity, decreased hematocrit, increased hemoglobin, purpura, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, vasculitis, contact dermatitis, injection site reactions, skin nodules, headache, leg cramps, sensory impairment, migraine, neuralgia, neuropathy, sensory anomalies, cerebral infarction, aseptic meningitis, ataxia, suicidal thoughts, loss of smell, loss of taste, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reactions, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, cholestasis, cholestatic hepatitis, jaundice, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rashes, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized bullous fixed drug eruption, fixed drug eruption, tubulointerstitial nephritis, nephrotic syndrome, microscopic lesion glomerulonephritis, menstrual disorders, female infertility, hallucinations, hearing loss, ear abnormalities, otalgia, hearing impairment, cholelithiasis, cholestatic hepatitis, vasculitis, nosebleeds, speech disorders, pneumonia, dyspnea, chest pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, shingles, low back pain, hearing loss

This medication should be stored in a tightly sealed container to protect it from air and moisture, ideally in a cool place between 15 degrees and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness.

Appearance

Capsules filled with white to pale yellow powder, upper and lower parts white.

Package unit

30 capsules/bottle, 100 capsules/bottle