Solive Tablet 10 mg (Solifenacin Succinate)

Adult dose

The usual recommended dose for adults (including elderly patients) is 5mg once daily. If necessary, the dose may be increased up to 10mg once daily. This drug may be taken irrespective of meals and should be swallowed whole with water. Dosage adjustment is required for the following patients. 1. Patients with renal impairment: No dose adjustment is required for patients with mild or moderate renal impairment (creatinine clearance>30ml/min). In patients with severe renal impairment (creatinine clearance≤30ml/min), administer with caution and do not exceed 5mg once daily. 2. Patients with hepatic impairment: No dose adjustment is required for patients with mild hepatic impairment. In patients with moderate hepatic impairment (Child-Pugh Class B), administer with caution and do not exceed 5mg once daily. 3. Patients receiving a strong cytochrome P450 3A4 (CYP3A4) inhibitor: For patients receiving ketoconazole or another strong CYP3A4 inhibitor (e.g., ritonavir, nelfinavir, itraconazole), limit the maximum daily dose to 5mg.

This medication should not be used in patients with urinary retention, severe gastrointestinal disease, myasthenia gravis, or narrow-angle glaucoma. Additionally, patients who are allergic to any of the ingredients in this medication, those undergoing hemodialysis, and patients with severe liver or kidney disorders should avoid administration. Caution is advised in patients at risk of urinary retention or with gastrointestinal obstruction or decreased gastrointestinal motility, and dosage should be limited in patients with severe kidney or liver disorders. While taking this medication, side effects such as dry mouth, constipation, blurred vision, urinary retention, and dry eyes may occur, and caution is required. In particular, dry mouth and constipation may occur more frequently with higher doses. This medication may affect driving or operating machinery, so care should be taken if symptoms occur. Furthermore, this medication may interact with certain medicines; therefore, it is advisable to consult a physician before taking it with other anticholinergic medications or strong CYP3A4 inhibitors. Women who are pregnant or breastfeeding should exercise caution when using this medication, and it is advisable to avoid use during breastfeeding. Safety in children has not been established, so it should not be administered to children. In case of overdose, symptoms such as headache, dizziness, drowsiness, and blurred vision may occur, and in severe cases, professional treatment may be necessary. Before taking this medication, it is essential to inform healthcare professionals about any existing diseases or medications, and to consult a doctor immediately if unusual symptoms occur.

• Dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• fecal impaction
• colonic obstruction
• intestinal obstruction
• vascular neurogenic edema
• nausea

This medication should be stored in a tightly closed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance

Bright pink circular film-coated tablet

Package unit

100 tablets/PTP [10 tablets/PTP packaging x 10], 30 tablets/bottle, 100 tablets/bottle